Emerging roles of antimicrobial peptides in innate immunity, neuronal function, and neurodegeneration

S Lee, N Silverman, FB Gao - Trends in Neurosciences, 2024 - cell.com
Antimicrobial peptides (AMPs), a collection of small proteins with important roles in classical
innate immunity, have been extensively studied in multiple organisms, particularly in …

Neuroinflammation catching nanobubbles for microglia-neuron unit modulation against epilepsy

X Wang, Y Liu, M Li, Y Ju, J Tang, T Chen, X Lin, N Gu… - Biomaterials, 2023 - Elsevier
Epilepsy is a common neurological disease caused by synchronous firing of hyperexcitable
neurons. Currently, patients with epilepsy are typically treated with antiseizure medicines …

[HTML][HTML] CRISPR/Cas9-mediated neuronal deletion of 5-lipoxygenase alleviates deficits in mouse models of epilepsy

Q Guan, Z Wang, K Zhang, Z Liu, H Zhou, D Cao… - Journal of Advanced …, 2024 - Elsevier
Introduction Our previous work reveals a critical role of activation of neuronal Alox5 in
exacerbating brain injury post seizures. However, whether neuronal Alox5 impacts the …

Evaluation of bioactive potentials in the crude flavonoid fraction from the leaves of Butea monosperma in vitro and in vivo in experimental models

R Bala, S Mehta, VC Roy, RC Roy, S Roy… - Indian Journal of …, 2023 - or.niscpr.res.in
Oxidative stress is responsible for the advent of seizure hence, antioxidants are used for the
treatment neurodegenerative ailments such as epilepsy. Profoundly, Butea monosperma …

Causal role of peripheral immune cells in epilepsy: A large-scale genetic correlation study

T Zhao, J Cui, S Lan, L Chu, S Tian, X Zhou - International …, 2024 - Elsevier
Background While an increasing number of researchers have focused on the correlation
between the immune system and epilepsy, the precise causal role of immune cells in …

ERK1/2 Regulates Epileptic Seizures by Modulating the DRP1‐Mediated Mitochondrial Dynamic

T Chen, J Yang, Y Zheng, X Zhou, H Huang… - Synapse, 2024 - Wiley Online Library
After seizures, the hyperactivation of extracellular signal‐regulated kinases (ERK1/2) causes
mitochondrial dysfunction. Through the guidance of dynamin‐related protein 1 (DRP1) …

[PDF][PDF] Neuronal malady in epileptic brain–Amendment with mushrooms

MA Rahman, AK Alpona, D Biswas… - Arch Neurol …, 2023 - researchgate.net
Epilepsy is a neurological disorder of the central nervous system usuallay manifested
through frequent seizures. Though epileptic symptoms had been recognized since ancient …

[引用][C] Life but not historical cohorts are required to calculate incidence, severity, and mortality of COVID-19 in epilepsy patients

J Finsterer - Seizure-European Journal of Epilepsy, 2023 - seizure-journal.com
Letter to the Editor We read with interest the article by Rider et al. on a retrospective cohort
study of the incidence, severity, and mortality of COVID-19 in 156 adult patients with …

Evaluation of bioactive potentials in the crude flavonoid fraction from the leaves of Butea monosperma (Lam.) Taub. in vitro and in vivo in experimental models

R Bala, S Mehta, VC Roy, RC Roy, S Roy, J Singh - 2023 - nopr.niscpr.res.in
Oxidative stress is responsible for the advent of seizure hence, antioxidants are used for the
treatment neurodegenerative ailments such as epilepsy. The Sacred tree, Butea …

[PDF][PDF] Isolating the neural circuitry of prickle-mediated epilepsy

A Lilienthal - 2023 - iro.uiowa.edu
Epilepsy is a neurological condition characterized by recurring seizures and is estimated to
affect 50 million individuals worldwide; however, one in three epilepsy patients are unable to …