Chemically engineering cells for precision medicine

Y Wang, Z Li, F Mo, TJ Chen-Mayfield, A Saini… - Chemical Society …, 2023 - pubs.rsc.org
Cell-based therapy holds great potential to address unmet medical needs and revolutionize
the healthcare industry, as demonstrated by several therapeutics such as CAR-T cell …

Advancing biomaterials of human origin for tissue engineering

FM Chen, X Liu - Progress in polymer science, 2016 - Elsevier
Biomaterials have played an increasingly prominent role in the success of biomedical
devices and in the development of tissue engineering, which seeks to unlock the …

[HTML][HTML] Collagen-based biomaterials for tissue engineering applications

R Parenteau-Bareil, R Gauvin, F Berthod - Materials, 2010 - mdpi.com
Collagen is the most widely distributed class of proteins in the human body. The use of
collagen-based biomaterials in the field of tissue engineering applications has been …

Dental pulp regeneration via cell homing

S Eramo, A Natali, R Pinna… - International endodontic …, 2018 - Wiley Online Library
The typical treatment for irreversibly inflamed/necrotic pulp tissue is root canal treatment. As
an alternative approach, regenerative endodontics aims to regenerate dental pulp‐like …

Tooth repair and regeneration: potential of dental stem cells

W Zhang, PC Yelick - Trends in molecular medicine, 2021 - cell.com
Tooth defects are an extremely common health condition that affects millions of individuals.
Currently used dental repair treatments include fillings for caries, endodontic treatment for …

A review on endogenous regenerative technology in periodontal regenerative medicine

FM Chen, J Zhang, M Zhang, Y An, F Chen, ZF Wu - Biomaterials, 2010 - Elsevier
Periodontitis is a globally prevalent inflammatory disease that causes the destruction of the
tooth-supporting apparatus and potentially leads to tooth loss. Currently, the methods to …

Homing of endogenous stem/progenitor cells for in situ tissue regeneration: promises, strategies, and translational perspectives

FM Chen, LA Wu, M Zhang, R Zhang, HH Sun - Biomaterials, 2011 - Elsevier
Stem cell-based therapy has been one of the best documented approaches in regenerative
medicine, promising cures for a multitude of diseases and disorders. However, the ex vivo …

Regeneration of dental-pulp-like tissue by chemotaxis-induced cell homing

JY Kim, X Xin, EK Moioli, J Chung, CH Lee… - … Engineering Part A, 2010 - liebertpub.com
Tooth infections or injuries involving dental pulp are treated routinely by root canal therapy.
Endodontically treated teeth are devitalized, susceptible to re-infections, fractures, and …

Incorporation of stromal cell-derived factor-1α in PCL/gelatin electrospun membranes for guided bone regeneration

W Ji, F Yang, J Ma, MJ Bouma, OC Boerman, Z Chen… - Biomaterials, 2013 - Elsevier
The goal of this work was to evaluate the effect of membrane functionalization with a
chemotactic factor on cell recruitment and bone formation in order to develop a bioactive …

Three-dimensional printed multiphase scaffolds for regeneration of periodontium complex

CH Lee, J Hajibandeh, T Suzuki, A Fan… - … Engineering Part A, 2014 - liebertpub.com
Tooth-supporting periodontium forms a complex with multiple tissues, including cementum,
periodontal ligament (PDL), and alveolar bone. In this study, we developed multiphase …