Cardiovascular disease and cancer are the 2 leading causes of death worldwide. Emerging
evidence suggests common mechanisms between cancer and cardiovascular disease …

Importance Low-dose aspirin is used for primary cardiovascular disease prevention and
may have benefits for colorectal cancer prevention. Objective To review the benefits and …

Aspirin (acetylsalicylic acid), the oldest synthetic drug, was originally used as an anti-
inflammatory medication. Being an irreversible inhibitor of COX (prostaglandin …

Abstract Background ASPirin in Reducing Events in the Elderly, a randomized, double-blind,
placebo-controlled trial of daily low-dose aspirin (100 mg) in older adults, showed an …

Platelet function can be modified by cancer cells to support tumor growth, causing
alterations in the delicate hemostatic equilibrium. Cancer-cell and platelet interactions are …

Importance Observational studies of survivors of breast cancer and prospective trials of
aspirin for cardiovascular disease suggest improved breast cancer survival among aspirin …

Purpose colorectal cancer (CRC) is one of the most commonly diagnosed cancers
worldwide. Some evidence has shown that aspirin can reduce the morbidity and mortality of …

Introduction: While the clinical merits of aspirin in secondary cardiovascular disease (CVD)
prevention remain undisputed, its role in primary prevention is controversial. Recently, three …

Background: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related
death worldwide, with about 841,000 new cases and 782,000 deaths annually. Given the …

Background and objective: Long-term aspirin use for the primary prevention of cancer
remains controversial, and variations in the effect of aspirin use on cancer outcomes by …