Small Schiff Base Molecules—A Possible Strategy to Combat Biofilm-Related Infections

M Coandă, C Limban, DC Nuță - Antibiotics, 2024 - mdpi.com
Microorganisms participating in the development of biofilms exhibit heightened resistance to
antibiotic treatment, therefore infections involving biofilms have become a problem in recent …

Novel Schiff base derivatives containing 4, 5-disubstituted thiazole as potential antibiofilm, anti-inflammatory and antioxidant agents: Green synthesis, molecular …

D Bhosale, A Narale, P Hadimani, M Kokane… - Journal of Molecular …, 2024 - Elsevier
We report the microwave-assisted (MW) green synthesis of some novel 4, 5 disubstituted
thiazole-containing Schiff base derivatives (SBs) as antibiofilm, anti-inflammatory, and …

Investigation of Newly Synthesized Fluorinated Isatin-Hydrazones by In Vitro Antiproliferative Activity, Molecular Docking, ADME Analysis, and e-Pharmacophore …

E Başaran, S Köprü, S Akkoç… - ACS Omega, 2024 - ACS Publications
In this study, we investigated the in vitro antiproliferative activities and performed
computational studies of newly synthesized fluorinated isatin-hydrazones. The chemical …

Sulfonyl hydrazone derivatives containing acetonaphtone as anticholinesterase inhibitors for the treatment of Alzheimer's: X-ray single-crystal analysis, and multifaced …

ÜÖ Özmen, S Alyar, EB Ayan, N Canbolat… - Journal of Molecular …, 2024 - Elsevier
In this study, the inhibitory activities of three different sulfonylhydrazone compounds (Anaf-
salesh, Anaf-salpsh, Anaf-salbsh) obtained by using different alkyl sulfonic acid hydrazide …

Synthesis, anticancer and antioxidant activities of novel heterocyclic phenolic hydrazone based derivatives: Investigation of DFT calculation, molecular docking and …

A Xing, P Zhu, B Zhang, J Lu, Y Zhang, D Zeng… - Journal of Molecular …, 2025 - Elsevier
In this research, the anticancer and antioxidant activities of a novel class of heterocyclic
phenolic hydrazone derivatives were investigated. The structure determination of the …

Azole rings linked to COX inhibitors via hydrazone bridge: Synthesis, stereochemical analysis, and investigation of antimicrobial activity

A Karagüzel, SB Uğur, Y Çetinkaya, ŞD Doğan… - Journal of Molecular …, 2024 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) alleviate inflammation and pain through the
inhibition of cyclooxygenase (COX) enzymes. Besides these widely recognized therapeutic …