TIL Therapy in Lung Cancer: Current Progress and Perspectives

W Hu, Y Bian, H Ji - Advanced Science, 2024 - Wiley Online Library
Lung cancer remains the most prevalent malignant tumor worldwide and is the leading
cause of cancer‐related mortality. Although immune checkpoint blockade has revolutionized …

[HTML][HTML] Prediction of prognosis and treatment response in ovarian cancer patients from histopathology images using graph deep learning: a multicenter retrospective …

Z Yang, Y Zhang, L Zhuo, K Sun, F Meng… - European Journal of …, 2024 - Elsevier
Background Ovarian cancer (OV) is a prevalent and deadly disease with high mortality rates.
The development of accurate prognostic tools and personalized therapeutic strategies is …

A comprehensive meta-analysis of tissue resident memory T cells and their roles in shaping immune microenvironment and patient prognosis in non-small cell lung …

A Shen, A Garrett, CC Chao, D Liu, C Cheng… - Frontiers in …, 2024 - frontiersin.org
Tissue-resident memory T cells (TRM) are a specialized subset of long-lived memory T cells
that reside in peripheral tissues. However, the impact of TRM-related immunosurveillance …

Integrated profiling identifies DXS253E as a potential prognostic marker in colorectal cancer

P Xing, H Hao, J Chen, X Qiao, T Song, X Yang… - Cancer Cell …, 2024 - Springer
Background Increasing evidence suggests that DXS253E is critical for cancer development
and progression, but the function and potential mechanism of DXS253E in colorectal cancer …

Assessment of PD-L1 expression and tumour infiltrating lymphocytes in early-stage non-small cell lung carcinoma with artificial intelligence algorithms

A Molero, S Hernandez, M Alonso… - Journal of Clinical …, 2024 - jcp.bmj.com
Aims To study programmed death ligand 1 (PD-L1) expression and tumour infiltrating
lymphocytes (TILs) in patients with early-stage non-small cell lung carcinoma (NSCLC) with …

Tissue-resident memory T cell signatures from single-cell analysis associated with better melanoma prognosis

C Jiang, CC Chao, J Li, X Ge, A Shen, V Jucaud… - Iscience, 2024 - cell.com
Tissue-resident memory T cells (T RM) are a specialized T cell population residing in
peripheral tissues. The presence and potential impact of T RM in the tumor immune …

Multi-omics pan-cancer analysis reveals the prognostic values and immunological functions of PPA2, with a spotlight on breast cancer

JN Zhang, BB Yang, LW Li, H Xu, B Wang… - Frontiers in …, 2024 - frontiersin.org
Background Recently, the role of inorganic pyrophosphatase 2 (PPA2) has been remaining
merely superficial in many tumors. Hence, the aim was to analyze the potential functions of …

The co‐location of CD14+ APOE+ cells and MMP7+ tumour cells contributed to worse immunotherapy response in non‐small cell lung cancer

G Fan, T Xie, L Tang, L Li, X Han… - Clinical and Translational …, 2024 - Wiley Online Library
Intra‐tumour immune infiltration is a crucial determinant affecting immunotherapy response
in non‐small cell lung cancer (NSCLC). However, its phenotype and related spatial structure …

MCT4 is an independent prognostic factor and affects immune cell infiltration in patients with colorectal liver oligometastases

J He, W Li, J Wang, X Wu, W Zhang, J Lin… - Clinical and …, 2024 - Springer
Abstract Background Monocarboxylate transporter 4 (MCT4) is a novel biomarker related to
the level of immune cell infiltration, but its impact on tumor immune microenvironment (TIME) …

A Glimpse Into the Future for Unresectable Stage III Non-Small Cell Lung Cancer

V Bartolomeo, F Cortiula, LEL Hendriks… - International Journal of …, 2024 - Elsevier
Conclusion The abundance of data from clinical trials and real-life studies, coupled with the
advancement of artificial intelligence tools, can aid in revamping our approach to treating …