[HTML][HTML] Current strategies for exosome cargo loading and targeting delivery

H Zeng, S Guo, X Ren, Z Wu, S Liu, X Yao - Cells, 2023 - mdpi.com
Extracellular vesicles (EVs) such as ectosomes and exosomes have gained attention as
promising natural carriers for drug delivery. Exosomes, which range from 30 to 100 nm in …

[HTML][HTML] Engineering exosome-based biomimetic nanovehicles for wound healing

A Joorabloo, T Liu - Journal of Controlled Release, 2023 - Elsevier
Complexity and difficulties in wound management are pressing concerns that affect patients'
quality of life and may result in tissue infection, necrosis, and loss of local and systemic …

[HTML][HTML] Polysaccharide hydrogel platforms as suitable carriers of liposomes and extracellular vesicles for dermal applications

LP Jahromi, M Rothammer, G Fuhrmann - Advanced Drug Delivery …, 2023 - Elsevier
Lipid-based nanocarriers have been extensively investigated for their application in drug
delivery. Particularly, liposomes are now clinically established for treating various diseases …

Current knowledge and future perspectives of exosomes as nanocarriers in diagnosis and treatment of diseases

Z Zou, H Li, G Xu, Y Hu, W Zhang… - International Journal of …, 2023 - Taylor & Francis
Exosomes, as natural nanocarriers, characterized with low immunogenicity, non-cytotoxicity
and targeted delivery capability, which have advantages over synthetic nanocarriers …

Significant enhancement of fibroblast migration, invasion, and proliferation by exosomes loaded with human fibroblast growth factor 1

MD Hade, CN Suire, Z Suo - ACS Applied Materials & Interfaces, 2024 - ACS Publications
Exosomes possess several inherent properties that make them ideal for biomedical
applications, including robust stability, biocompatibility, minimal immunogenicity, and the …

Small extracellular vesicles: Yields, functionalization and applications in diabetic wound management

X Liu, Q Wei, Z Sun, S Cui, X Wan, Z Chu… - Interdisciplinary …, 2023 - Wiley Online Library
Diabetic wounds have imposed a significant burden on both patients and society with
prolonged healing processes hindered by dysfunctional skin repair cells. Small extracellular …

Standardization approaches for extracellular vesicle loading with oligonucleotides and biologics

J Roerig, M Schulz‐Siegmund - Small, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are widely recognized for their potential as drug delivery
systems. EVs are membranous nanoparticles shed from cells. Among their natural features …

[HTML][HTML] Roles of extracellular vesicles on the progression and metastasis of hepatocellular carcinoma

TW Seay, Z Suo - Cells, 2023 - mdpi.com
Liver cancer is a global health challenge as it is the third leading cause of cancer death
worldwide. Hepatocellular carcinoma (HCC) is the most common type of liver cancer and is …

[HTML][HTML] Enhanced lysosomal escape of cell penetrating peptide-functionalized metal–organic frameworks for co-delivery of survivin siRNA and oridonin

M Cai, Y Yao, D Yin, R Zhu, T Fu, J Kong… - Journal of Colloid and …, 2023 - Elsevier
In recent years, small interfering RNA (siRNA) has been widely used in the treatment of
human diseases, especially tumors, and has shown great appeal. However, the clinical …

[HTML][HTML] Extracellular vesicles for therapeutic nucleic acid delivery: loading strategies and challenges

A Oshchepkova, M Zenkova, V Vlassov - International Journal of …, 2023 - mdpi.com
Extracellular vesicles (EVs) are membrane vesicles released into the extracellular milieu by
cells of various origins. They contain different biological cargoes, protecting them from …