Targeting PI3K/Akt signaling in prostate cancer therapy
M Hashemi, A Taheriazam, P Daneii… - Journal of Cell …, 2023 - Springer
Urological cancers have obtained much attention in recent years due to their mortality and
morbidity. The most common and malignant tumor of urological cancers is prostate cancer …
morbidity. The most common and malignant tumor of urological cancers is prostate cancer …
Non-coding RNAs and macrophage interaction in tumor progression
M Entezari, M Sadrkhanloo, M Rashidi, SE Asnaf… - Critical reviews in …, 2022 - Elsevier
The macrophages are abundantly found in TME and their M2 polarization is in favor of tumor
malignancy. On the other hand, non-coding RNAs (ncRNAs) can modulate macrophage …
malignancy. On the other hand, non-coding RNAs (ncRNAs) can modulate macrophage …
[HTML][HTML] Factors influencing degradation kinetics of mRNAs and half-lives of microRNAs, circRNAs, lncRNAs in blood in vitro using quantitative PCR
C Wang, H Liu - Scientific Reports, 2022 - nature.com
RNAs are rapidly degraded in samples and during collection, processing and testing. In this
study, we used the same method to explore the half-lives of different RNAs and the …
study, we used the same method to explore the half-lives of different RNAs and the …
[HTML][HTML] From omics to multi-omics approaches for in-depth analysis of the molecular mechanisms of prostate cancer
E Nevedomskaya, B Haendler - International Journal of Molecular …, 2022 - mdpi.com
Cancer arises following alterations at different cellular levels, including genetic and
epigenetic modifications, transcription and translation dysregulation, as well as metabolic …
epigenetic modifications, transcription and translation dysregulation, as well as metabolic …
[HTML][HTML] circPHF16 suppresses prostate cancer metastasis via modulating miR-581/RNF128/Wnt/β-catenin pathway
L Ding, Y Lin, X Chen, R Wang, H Lu, H Wang, W Luo… - Cellular …, 2023 - Elsevier
Circular RNAs (circRNAs) have been recognized as important regulators in tumorigenesis.
However, the specific role of circRNAs in prostate cancer is still largely unknown. Here, we …
However, the specific role of circRNAs in prostate cancer is still largely unknown. Here, we …
[HTML][HTML] Current therapeutic modalities and chemopreventive role of natural products in liver cancer: Progress and promise
Liver cancer is a severe concern for public health officials since the clinical cases are
increasing each year, with an estimated 5-year survival rate of 30%–35% after diagnosis …
increasing each year, with an estimated 5-year survival rate of 30%–35% after diagnosis …
[HTML][HTML] Androgen-Responsive Oncogenic lncRNA RP11-1023L17. 1 Enhances c-Myc protein stability in prostate cancer
W Huang, Q Chen, Y Lu, Z Kong, X Wan… - International Journal of …, 2022 - mdpi.com
Long noncoding RNAs (lncRNAs) have been found as novel participants in the
pathophysiology of prostate cancer (PCa), which is predominantly regulated by androgen …
pathophysiology of prostate cancer (PCa), which is predominantly regulated by androgen …
[HTML][HTML] An emerging link between lncRNAs and cancer sex dimorphism
The prevalence and progression of cancer differ in males and females, and thus, sexual
dimorphism in tumor development directly impacts clinical research and medicine. Long non …
dimorphism in tumor development directly impacts clinical research and medicine. Long non …
Androgen‐repressed lncRNA LINC01126 drives castration‐resistant prostate cancer by regulating the switch between O‐GlcNAcylation and phosphorylation of …
Y Cai, M Chen, Y Gong, G Tang, Z Shu… - Clinical and …, 2024 - Wiley Online Library
Abstract Background Prostate cancer (PCa) initially shows satisfactory response to therapies
targeting the androgen receptor (AR). However, progression to a castration‐resistant stage …
targeting the androgen receptor (AR). However, progression to a castration‐resistant stage …
Non-coding RNAs in gynecologic cancer
A Solati, S Thvimi, SH Khatami, Z Shabaninejad… - Clinica Chimica …, 2023 - Elsevier
The term “gynecologic cancer” pertains to neoplasms impacting the reproductive tissues and
organs of women encompassing the endometrium, vagina, cervix, uterus, vulva, and …
organs of women encompassing the endometrium, vagina, cervix, uterus, vulva, and …