The interface of protein structure, protein biophysics, and molecular evolution
Abstract The interface of protein structural biology, protein biophysics, molecular evolution,
and molecular population genetics forms the foundations for a mechanistic understanding of …
and molecular population genetics forms the foundations for a mechanistic understanding of …
Biophysical models of protein evolution: understanding the patterns of evolutionary sequence divergence
For decades, rates of protein evolution have been interpreted in terms of the vague concept
of functional importance. Slowly evolving proteins or sites within proteins were assumed to …
of functional importance. Slowly evolving proteins or sites within proteins were assumed to …
Trends in substitution models of molecular evolution
M Arenas - Frontiers in genetics, 2015 - frontiersin.org
Substitution models of evolution describe the process of genetic variation through fixed
mutations and constitute the basis of the evolutionary analysis at the molecular level. Almost …
mutations and constitute the basis of the evolutionary analysis at the molecular level. Almost …
A combined empirical and mechanistic codon model
A Doron-Faigenboim, T Pupko - Molecular biology and evolution, 2007 - academic.oup.com
The evolutionary selection forces acting on a protein are commonly inferred using
evolutionary codon models by contrasting the rate of synonymous to nonsynonymous …
evolutionary codon models by contrasting the rate of synonymous to nonsynonymous …
The evolution of protein structures and structural ensembles under functional constraint
Protein sequence, structure, and function are inherently linked through evolution and
population genetics. Our knowledge of protein structure comes from solved structures in the …
population genetics. Our knowledge of protein structure comes from solved structures in the …
Protein evolution along phylogenetic histories under structurally constrained substitution models
Motivation: Models of molecular evolution aim at describing the evolutionary processes at
the molecular level. However, current models rarely incorporate information from protein …
the molecular level. However, current models rarely incorporate information from protein …
The quest for natural selection in the age of comparative genomics
M Anisimova, DA Liberles - Heredity, 2007 - nature.com
Continued genome sequencing has fueled progress in statistical methods for understanding
the action of natural selection at the molecular level. This article reviews various statistical …
the action of natural selection at the molecular level. This article reviews various statistical …
[图书][B] Codon evolution: mechanisms and models
GM Cannarozzi, A Schneider - 2012 - books.google.com
Codon-based models of evolution are a relatively new addition to the toolkit of
computational biologists, and in recent years remarkable progress has been made in this …
computational biologists, and in recent years remarkable progress has been made in this …
Biophysical and structural considerations for protein sequence evolution
JA Grahnen, P Nandakumar, J Kubelka… - BMC evolutionary …, 2011 - Springer
Background Protein sequence evolution is constrained by the biophysics of folding and
function, causing interdependence between interacting sites in the sequence. However …
function, causing interdependence between interacting sites in the sequence. However …
[PDF][PDF] Interaksi Molekuler Amonium Hidroksida
AP Lubis, R Zainul - 2018 - scholar.archive.org
Amonium hidroksida adalah larutan amonia didalam air dengan rumus NH4OH. Amonium
hidroksida merupakan senyawa yang tidak berwarna dan memiliki bau yang sangat tajam …
hidroksida merupakan senyawa yang tidak berwarna dan memiliki bau yang sangat tajam …