Actin binding proteins: their ups and downs in metastatic life

SR Gross - Cell adhesion & migration, 2013 - Taylor & Francis
In order to metastasize away from the primary tumor site and migrate into adjacent tissues,
cancer cells will stimulate cellular motility through the regulation of their cytoskeletal …

[HTML][HTML] PRKCSH contributes to TNFSF resistance by extending IGF1R half-life and activation in lung cancer

GC Shin, HM Lee, N Kim, SU Seo, KP Kim… - … & Molecular Medicine, 2024 - nature.com
Tumor necrosis factor superfamily (TNFSF) resistance contributes to the development and
progression of tumors and resistance to various cancer therapies. Tumor-intrinsic alterations …

LncRNA XIST promotes chemoresistance of breast cancer cells to doxorubicin by sponging miR‐200c‐3p to upregulate ANLN

M Zhang, F Wang, Z Xiang, T Huang… - Clinical and …, 2020 - Wiley Online Library
The resistance of breast cancer cells to drugs is a major obstacle to effective cancer
chemotherapy. Here, we study the function mechanisms of long non‐coding RNA XIST in …

[HTML][HTML] Risk assessment, disease prevention and personalised treatments in breast cancer: is clinically qualified integrative approach in the horizon?

O Golubnitschaja, K Yeghiazaryan, V Costigliola… - EPMA Journal, 2013 - Springer
Breast cancer is a multifactorial disease. A spectrum of internal and external factors
contributes to the disease promotion such as a genetic predisposition, chronic inflammatory …

Impedimetric detection of calreticulin by a disposable immunosensor modified with a single-walled carbon nanotube-conducting polymer nanocomposite

EB Aydın, M Aydın, MK Sezgintürk - ACS Biomaterials Science & …, 2022 - ACS Publications
A label-free impedimetric immunosensing system was constructed for ultrasensitive
determination of the calreticulin (CALR) biological marker in human serum samples utilizing …

[HTML][HTML] Regulation of NADPH oxidase 5 by protein kinase C isoforms

F Chen, Y Yu, S Haigh, J Johnson, R Lucas, DW Stepp… - PloS one, 2014 - journals.plos.org
NADPH oxidase5 (Nox5) is a novel Nox isoform which has recently been recognized as
having important roles in the pathogenesis of coronary artery disease, acute myocardial …

[PDF][PDF] PDIA3 and PDIA6 gene expression as an aggressiveness marker in primary ductal breast cancer

FS Ramos, LT Serino, CM Carvalho, RS Lima… - Genet Mol …, 2015 - funpecrp.com.br
Changes in the expression of the protein disulfide isomerase genes PDIA3and PDIA6may
increase endoplasmic reticulum stress, leading to cellular instability and neoplasia. We …

[HTML][HTML] PRKCSH serves as a potential immunological and prognostic biomarker in pan-cancer

Q Wang, X Wang, J Li, T Yin, Y Wang, L Cheng - Scientific Reports, 2024 - nature.com
Protein kinase C substrate 80K-H (PRKCSH) plays a crucial role in the protein N-terminal
glycosylation process, with emerging evidence implicating its involvement in tumorigenesis …

[HTML][HTML] PRKCSH contributes to tumorigenesis by selective boosting of IRE1 signaling pathway

GC Shin, SU Moon, HS Kang, HS Choi, HD Han… - Nature …, 2019 - nature.com
Unfolded protein response (UPR) is an adaptive mechanism that aims at restoring ER
homeostasis under severe environmental stress. Malignant cells are resistant to …

Potential role of PRKCSH in lung cancer: bioinformatics analysis and a case study of Nano ZnO

R Lei, M Zhou, S Zhang, J Luo, C Qu, Y Wang, P Guo… - Nanoscale, 2022 - pubs.rsc.org
PRKCSH, also known as glucosidase II beta, functions as a contributor to lung
tumorigenesis by regulating the cell cycle in a p53-dependent manner under severe …