Dysregulation of inflammasome activation in glioma
Gliomas are the most common brain tumors characterized by complicated heterogeneity.
The genetic, molecular, and histological pathology of gliomas is characterized by high neuro …
The genetic, molecular, and histological pathology of gliomas is characterized by high neuro …
Deconvolution of cell type-specific drug responses in human tumor tissue with single-cell RNA-seq
Background Preclinical studies require models that recapitulate the cellular diversity of
human tumors and provide insight into the drug sensitivities of specific cellular populations …
human tumors and provide insight into the drug sensitivities of specific cellular populations …
Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis
Background Multiple glioblastoma studies have described a mesenchymal (MES) state, with
each study defining the MES program by distinct sets of genes and highlighting distinct …
each study defining the MES program by distinct sets of genes and highlighting distinct …
Modeling nervous system tumors with human stem cells and organoids
J Duan, Y Wang - Cell Regeneration, 2023 - Springer
Nervous system cancers are the 10th leading cause of death worldwide, many of which are
difficult to diagnose and exhibit varying degrees of treatment resistance. The limitations of …
difficult to diagnose and exhibit varying degrees of treatment resistance. The limitations of …
[PDF][PDF] Genetic characterization of stem cell-like cancer cell in the peri-tumoral regions and proliferative lymphocyte in the peripheral blood of patients with …
R Yang, G Huang, J Guo, Y Li, H Song, K Li, G Yi, Z Lin… - 2020 - pdfs.semanticscholar.org
The glioblastoma (GBM) recurrence rate is high, despite multimodal treatment including
surgery, radiotherapy, chemotherapy, and immunotherapy. Most recurrences occur at the …
surgery, radiotherapy, chemotherapy, and immunotherapy. Most recurrences occur at the …
Discovery of peculiar cells in the peri-tumoral regions and peripheral blood of glioblastoma patients by single cell RNA-sequencing
R Yang, G Huang, J Guo, Y Li, H Song, K Li, G Yi, Z Lin… - bioRxiv, 2020 - biorxiv.org
Recurrence is almost inevitable in glioblastoma (GBM) patients even after aggressive
multimodal therapies. Most recurrences occur at the resection margin that is outside GBM's …
multimodal therapies. Most recurrences occur at the resection margin that is outside GBM's …