Neuromyelitis optica (NMO) is an inflammatory CNS syndrome distinct from multiple
sclerosis (MS) that is associated with serum aquaporin-4 immunoglobulin G antibodies …

B cells are essential components of the adaptive immune system and have important roles
in the pathogenesis of several central nervous system (CNS) diseases. Besides producing …

Objective We characterised the clinical course, treatment and outcomes in 59 patients with
relapsing myelin oligodendrocyte glycoprotein (MOG) antibody-associated demyelination …

Neuromyelitis optica spectrum disorder (NMOSD) is an uncommon antibody-mediated
disease of the central nervous system. Long segments of spinal cord inflammation (myelitis) …

Since its initial reports in the 19th century, neuromyelitis optica (NMO) had been thought to
involve only the optic nerves and spinal cord. However, the discovery of highly specific anti …

Neuromyelitis optica spectrum disorders (NMOSD) are autoantibody mediated chronic
inflammatory diseases. Serum antibodies (Abs) against the aquaporin-4 water channel lead …

Acute optic neuritis is the most common optic neuropathy affecting young adults. Exciting
developments have occurred over the past decade in understanding of optic neuritis …

The understanding of neuromyelitis optica spectrum disorder (NMOSD) has evolved
substantially since its initial description over a century ago. The discovery in 2004 of a …

Neuromyelitis optica (NMO, Devic's syndrome), long considered a clinical variant of multiple
sclerosis, is now regarded as a distinct disease entity. Major progress has been made in the …

PURPOSE OF REVIEW This article discusses the clinical presentation, evaluation, and
management of the patient with optic neuritis. Initial emphasis is placed on clinical history …