Peptide-based molecules for the disruption of bacterial Hsp70 chaperones
A Richards, TJ Lupoli - Current Opinion in Chemical Biology, 2023 - Elsevier
DnaK is a chaperone that aids in nascent protein folding and the maintenance of proteome
stability across bacteria. Due to the importance of DnaK in cellular proteostasis, there have …
stability across bacteria. Due to the importance of DnaK in cellular proteostasis, there have …
HtpG—A Major Virulence Factor and a Promising Vaccine Antigen against Mycobacterium tuberculosis
R Berisio, G Barra, V Napolitano, M Privitera… - Biomolecules, 2024 - mdpi.com
Tuberculosis (TB) is the leading global cause of death f rom an infectious bacterial agent.
Therefore, limiting its epidemic spread is a pressing global health priority. The chaperone …
Therefore, limiting its epidemic spread is a pressing global health priority. The chaperone …
Bacterial J‐Domains with C‐Terminal Tags Contact the Substrate Binding Domain of DnaK and Sequester Chaperone Activity
B Nelson, N Soper, TJ Lupoli - ChemBioChem, 2023 - Wiley Online Library
Functional interactions between the molecular chaperone DnaK and cofactor J‐proteins
(DnaJs), as well as their homologs, are crucial to the maintenance of proteostasis across cell …
(DnaJs), as well as their homologs, are crucial to the maintenance of proteostasis across cell …
Characterization of Bacterial Chaperones and Rhamnosyltransferases Involved in Bacterial Infection of the Host
AP Harnagel - 2023 - search.proquest.com
Bacterial infection of the host requires systems of proteins that function in concert to enable
interactions host membranes and survival under stressful conditions. Cellular protein …
interactions host membranes and survival under stressful conditions. Cellular protein …