Cytokine regulation of endothelial cell function: from molecular level to the bedside

A Mantovani, F Bussolino, M Introna - Immunology today, 1997 - cell.com
Endothelial cells (ECs) participate in inflammatory and immune reactions by producing and
responding to cytokines. The molecular basis underlying the functional reprograming of …

Leukemia-inhibitory factor—neuroimmune modulator of endocrine function

CJ Auernhammer, S Melmed - Endocrine reviews, 2000 - academic.oup.com
Leukemia-inhibitory factor (LIF) is a pleiotropic cytokine expressed by multiple tissue types.
The LIF receptor shares a common gp130 receptor subunit with the IL-6 cytokine …

A newly discovered class of human hematopoietic cells with SCID-repopulating activity

M Bhatia, D Bonnet, B Murdoch, OI Gan, JE Dick - Nature medicine, 1998 - nature.com
The detection of primitive hematopoietic cells based on repopulation of immune-deficient
mice is a powerful tool to characterize the human stem-cell compartment. Here, we identify a …

Induction of astrocyte differentiation by endothelial cells

H Mi, H Haeberle, BA Barres - Journal of Neuroscience, 2001 - Soc Neuroscience
Here we have investigated the mechanisms that control astrocyte differentiation within the
developing rat optic nerve. Astrocytes are normally generated by astrocyte precursor cells …

Regulation of hematopoiesis by microvascular endothelium

S Rafii, R Mohle, F Shapiro, BM Frey… - Leukemia & …, 1997 - Taylor & Francis
The bone marrow microenvironment is a complex three dimensional structure where
hematopoietic stem cells proliferate, mature, migrate into the sinusoidal space, and enter the …

Endothelial cell biology: role in the inflammatory response

M Pate, V Damarla, DS Chi, S Negi… - Advances in clinical …, 2010 - Elsevier
Human endothelial cells are multifunctional cells that line blood vessels and are capable of
secreting a variety of biologically active mediators. They normally maintain vascular …

Cytokine activation of endothelial cells: new molecules for an old paradigm

A Mantovani, S Sozzani, A Vecchi… - Thrombosis and …, 1997 - thieme-connect.com
EPO G. CSF Chemoklnes FGF Endothelial cells (EC) have long considered little more ttran
a'layer of nucleated cellophane', endowed with negative properties, the most important of …

Leukemia inhibitory factor: part of a large ingathering family

JL Taupin, V Pitard, J Dechanet, V Miossec… - International reviews …, 1998 - Taylor & Francis
Leukemia Inhibitory Factor (LIF) has a wide variety of biological activities. It regulates the
differentiation of embryonic stem cells, neural cells, osteoblasts, adipocytes, hepatocytes …

The angioregulatory cytokine network in human acute myeloid leukemia-from leukemogenesis via remission induction to stem cell transplantation.

H Reikvam, KJ Hatfield, H Fredly, I Nepstad… - European cytokine …, 2012 - europepmc.org
Acute myeloid leukemia (AML) is characterized by bone marrow accumulation of immature
leukemic blast cells. Conventional AML treatment includes induction chemotherapy to …

[PDF][PDF] Regulation of endothelial cell function by pro-and anti-inflammatory cytokines

A Mantovani, C Garlanda, M Introna… - Transplantation …, 1998 - academia.edu
ENDOTHELIAL cells (EC) have long been considered a “passive” lining of blood vessels,
endowed with negative properties, the most important one being that of representing a …