Novel insights into pituitary tumorigenesis: genetic and epigenetic mechanisms
V Srirangam Nadhamuni, M Korbonits - Endocrine reviews, 2020 - academic.oup.com
Substantial advances have been made recently in the pathobiology of pituitary tumors.
Similar to many other endocrine tumors, over the last few years we have recognized the role …
Similar to many other endocrine tumors, over the last few years we have recognized the role …
[HTML][HTML] Molecular mechanisms of pituitary cell plasticity
GV Childs, AM MacNicol, MC MacNicol - Frontiers in Endocrinology, 2020 - frontiersin.org
The mechanisms that mediate plasticity in pituitary function have long been a subject of
vigorous investigation. Early studies overcame technical barriers and challenged conceptual …
vigorous investigation. Early studies overcame technical barriers and challenged conceptual …
The use of mass spectrometry in a proteome‐centered multiomics study of human pituitary adenomas
N Li, DM Desiderio, X Zhan - Mass Spectrometry Reviews, 2022 - Wiley Online Library
A pituitary adenoma (PA) is a common intracranial neoplasm, and is a complex, chronic, and
whole‐body disease with multicausing factors, multiprocesses, and multiconsequences. It is …
whole‐body disease with multicausing factors, multiprocesses, and multiconsequences. It is …
[HTML][HTML] The first pituitary proteome landscape from matched anterior and posterior lobes for a better understanding of the pituitary gland
To date, very few mass spectrometry (MS)–based proteomics studies are available on the
anterior and posterior lobes of the pituitary. In the past, MS-based investigations have …
anterior and posterior lobes of the pituitary. In the past, MS-based investigations have …
[HTML][HTML] Adaptation of the porcine pituitary transcriptome, spliceosome and editome during early pregnancy
The physiological mechanisms of the porcine reproduction are relatively well-known.
However, transcriptomic changes and the mechanisms accompanying transcription and …
However, transcriptomic changes and the mechanisms accompanying transcription and …
Recent advances in proteomics and its implications in pituitary endocrine disorders
A Banerjee, A Goel, A Shah, S Srivastava - Biochimica et Biophysica Acta …, 2021 - Elsevier
Pituitary adenoma is considered as one of the most frequent intracranial tumors having
salient impact on human health such as mass effects, hypopituitarism and visual defects etc …
salient impact on human health such as mass effects, hypopituitarism and visual defects etc …
[HTML][HTML] Quantitative analysis of proteome in non-functional pituitary adenomas: clinical relevance and potential benefits for the patients
T Cheng, Y Wang, M Lu, X Zhan, T Zhou, B Li… - Frontiers in …, 2019 - frontiersin.org
Background: Non-functional pituitary adenoma (NFPA) is a common tumor that occurs in the
pituitary gland, and generally without any symptoms at its early stage and without clinical …
pituitary gland, and generally without any symptoms at its early stage and without clinical …
[HTML][HTML] Proteomic response of rat pituitary under chronic mild stress reveals insights into vulnerability and resistance to anxiety or depression
F Tian, D Liu, J Chen, W Liao, W Gong, R Huang… - Frontiers in …, 2021 - frontiersin.org
Chronic stress as one of the most significant risk factor can trigger overactivity of
hypothalamic-pituitary-adrenal (HPA) axis in depression as well as anxiety. Yet, the shared …
hypothalamic-pituitary-adrenal (HPA) axis in depression as well as anxiety. Yet, the shared …
Integrated view of baseline protein expression in human tissues
A Prakash, D García-Seisdedos, S Wang… - Journal of Proteome …, 2022 - ACS Publications
The availability of proteomics datasets in the public domain, and in the PRIDE database, in
particular, has increased dramatically in recent years. This unprecedented large-scale …
particular, has increased dramatically in recent years. This unprecedented large-scale …
[PDF][PDF] 以表型组为重心的垂体瘤多组学研究
郑培贤, 李娜, 詹显全 - … of Shandong First Medical University & …, 2022 - researchgate.net
垂体瘤是常见的, 慢性的, 复杂性的颅内肿瘤, 是一种多病因, 多过程, 多后果的全身性疾病.
传统的单因素模型很难阐明垂体瘤的分子机制, 而随着多组学和系统生物学的迅速发展 …
传统的单因素模型很难阐明垂体瘤的分子机制, 而随着多组学和系统生物学的迅速发展 …