The glutamate and dopamine hypotheses are leading theories of the pathoaetiology of
schizophrenia. Both were initially based on indirect evidence from pharmacological studies …

Schizophrenia remains a major burden on patients and society. The dopamine hypothesis
attempts to explain the pathogenic mechanisms of the disorder, and the …

Despite an increasing number of published voxel based morphometry studies of
schizophrenia, there has been no adequate attempt to examine gray (GM) and white matter …

BACKGROUND: Magnetic resonance imaging studies have shown that structural brain
abnormalities are present in both schizophrenia and bipolar disorder. Most previous studies …

Objective: Although brain changes in schizophrenia have been proposed to mirror those
found with advancing age, the trajectory of gray matter and white matter changes during the …

We used data from studies of copy-number variants (CNVs), single-gene associations,
growth-signaling pathways, and intermediate phenotypes associated with brain growth to …

BackgroundRecent evidence from genetic and familial studies revitalized the debate
concerning the validity of the distinction between schizophrenia and bipolar disorder …

Although many pathogenic copy number variations (CNVs) are associated with
neuropsychiatric diseases, few of them have been functionally characterised. Here we report …

ZNF804A is one of the strongest candidate genes for schizophrenia (SZ), yet its function and
role in disease pathophysiology are largely unknown. The only in vivo endophenotype study …

Mental time travel (MTT) abilities could be particularly compromised in schizophrenic
patients due to a deficit of the cognitive processes at the basis of remembering the past and …