This narrative review examines the possible role of microglial cells, first, in
neuroinflammation and, second, in schizophrenia, depression, and suicide. Recent research …

The brainstem is a neglected brain area in neurodegenerative diseases, including
Alzheimer's and Parkinson's disease, frontotemporal lobar degeneration and autonomic …

BACKGROUND: Several lines of evidence implicate 5-hydroxytryptamine (5-HT, serotonin)
in the pathophysiology of mood disorders and suicide. However, it is unclear whether these …

Serotonin is an important neurotransmitter that broadly participates in various biological
processes. While serotonin deficiency has been associated with multiple pathological …

Hyperinnervation of the striatum by serotoninergic (5-HT) terminals occurs after destruction
of the dopaminergic nigro-striatal pathway. Recent studies have suggested that non …

Neurodegenerative diseases such as Parkinson's disease (PD), frontal lobe dementia (FLD)
and diffuse Lewy-body dementia (DLBD) have diverse neuropathologic features. Here we …

Background Aberrant resting-state functional connectivity is a neuropathological feature of
schizophrenia (SCZ). Prior investigations into functional connectivity abnormalities have …

The main goal of the present study was to evaluate binding to serotonin in the neocortex
surrounding the epileptic focus of patients with mesial temporal lobe epilepsy (MTLE) …

The central serotonergic system is implicated in the pathogenesis of schizophrenia, where
the imbalance between dopamine, serotonin and glutamate plays a key pathophysiological …

Despite evidence for an abnormality of noradrenergic function in schizophrenia, it remains
unclear whether the number of noradrenergic neurones is normal in patients with the …