Background: White matter hyperintensities of presumed vascular origin (WMH) are a
common finding in elderly people and a growing social malady in the aging western …

Abstract The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of
Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic …

Opinion statement Cerebral small vessel disease (SVD) is characterised by damage to deep
grey and white matter structures of the brain and is responsible for a diverse range of clinical …

Research has suggested that the retinal vasculature may act as a surrogate marker for
diseased cerebral vessels. Retinal vascular parameters were measured using Vessel …

Background Optical coherence tomography angiography (OCTA) is a novel and noninvasive
technique for the quantitative assessment of retinal microvascular perfusion. Since the …

Background and purpose As one common feature of cerebral small vascular disease
(cSVD), white matter lesions (WMLs) could lead to reduction in brain function. Using a …

Purpose The retina provides biomarkers of neuronal and vascular health that offer promising
insights into cognitive ageing, mild cognitive impairment and dementia. This article …

Background: Over recent years, some researchers believe that diabetic nephropathy (DN)
and diabetic retinopathy (DR) both independently increase the incidence of brain diseases …

Introduction We explored the longitudinal relationship between retinal vascular features and
dementia incidence over 10 years. Methods Among 584 participants from the Three‐City …

Methods: Fundus photographs from 4309 participants of the Gutenberg Health Study were
assessed using the 'retinal vessel analyzer'software (IMEDOS). We generated age and sex …