Breast cancer heterogeneity and its implication in personalized precision therapy
L Guo, D Kong, J Liu, L Zhan, L Luo, W Zheng… - … hematology & oncology, 2023 - Springer
Breast cancer heterogeneity determines cancer progression, treatment effects, and
prognosis. However, the precise mechanism for this heterogeneity remains unknown owing …
prognosis. However, the precise mechanism for this heterogeneity remains unknown owing …
Receptor conversion in distant breast cancer metastases: a systematic review and meta-analysis
WAME Schrijver, KPM Suijkerbuijk… - JNCI: Journal of the …, 2018 - academic.oup.com
Background In metastatic breast cancer, hormone and/or human epidermal growth factor
receptor 2 (HER2)–targeted therapy decision-making is still largely based on tissue …
receptor 2 (HER2)–targeted therapy decision-making is still largely based on tissue …
Comprehensive profiling of poor-risk paired primary and recurrent triple-negative breast cancers reveals immune phenotype shifts
KE Hutchinson, SE Yost, CW Chang, RM Johnson… - Clinical Cancer …, 2020 - AACR
Purpose: Emerging data suggest immune checkpoint inhibitors have reduced efficacy in
heavily pretreated triple-negative breast cancers (TNBC), but underlying mechanisms are …
heavily pretreated triple-negative breast cancers (TNBC), but underlying mechanisms are …
Neoadjuvant therapy for breast cancer as a model for translational research
Neoadjuvant therapy, where patients receive systemic therapy before surgical removal of
the tumour, can downstage tumours allowing breast-conserving surgery, rather than …
the tumour, can downstage tumours allowing breast-conserving surgery, rather than …
CCNE1 amplification is associated with poor prognosis in patients with triple negative breast cancer
ZM Zhao, SE Yost, KE Hutchinson, SM Li, YC Yuan… - BMC cancer, 2019 - Springer
Background Triple negative breast cancer (TNBC) is aggressive with limited treatment
options upon recurrence. Molecular discordance between primary and metastatic TNBC has …
options upon recurrence. Molecular discordance between primary and metastatic TNBC has …
Prognostic value of stromal type IV collagen expression in small invasive breast cancers
M Jansson, J Lindberg, G Rask, J Svensson… - Frontiers in Molecular …, 2022 - frontiersin.org
Breast cancer is the most common cause of cancer death among women worldwide.
Localized breast cancer can be cured by surgery and adjuvant therapy, but mortality …
Localized breast cancer can be cured by surgery and adjuvant therapy, but mortality …
Identification of FOXM1 as a specific marker for triple-negative breast cancer
Y Tan, Q Wang, Y Xie, X Qiao… - International …, 2018 - spandidos-publications.com
The present study aimed to identify the therapeutic role of the forkhead box M1 (FOXM1)-
associated pathway in triple-negative breast cancer (TNBC). Using a Cancer Landscapes …
associated pathway in triple-negative breast cancer (TNBC). Using a Cancer Landscapes …
New generation breast cancer cell lines developed from patient-derived xenografts
Background Breast cancer is a highly heterogeneous disease characterized by multiple
histologic and molecular subtypes. While a myriad of breast cancer cell lines have been …
histologic and molecular subtypes. While a myriad of breast cancer cell lines have been …
Discordances in ER, PR, and HER2 between primary breast cancer and brain metastasis
J Jung, SH Lee, M Park, JH Youn, SH Shin… - Journal of Neuro …, 2018 - Springer
When distant metastases are discovered, it is important to determine receptor profiles of
these lesions through histologic examination. However, brain metastasis sites are difficult to …
these lesions through histologic examination. However, brain metastasis sites are difficult to …
Receptor discordance in metastatic breast cancer; a review of clinical and genetic subtype alterations from primary to metastatic disease
Purpose Receptor and subtype discordance between primary breast tumours and
metastases is a frequently reported phenomenon. The aim of this article is to review the …
metastases is a frequently reported phenomenon. The aim of this article is to review the …