An ideal animal model of atherosclerosis resembles human anatomy and pathophysiology
and has the potential to be used in medical and pharmaceutical research to obtain results …

Background—Atherosclerotic lesions are predominantly observed in curved arteries and
near side branches, where low or oscillatory shear stress patterns occur, suggesting a …

Atherosclerosis is the leading cause of morbidity and mortality in the US, and is a
multifactorial disease that preferentially occurs in regions of the arterial tree exposed to …

Background—Inflammation plays an important role in atherogenesis. The toll-like receptor 4
(TLR4) is the receptor for bacterial lipopolysaccharides and also recognizes cellular …

Background—Toll-like receptor 4 (Tlr4) is the receptor for exogenous lipopolysaccharides
(LPS). Expression of endogenous Tlr4 ligands, heat shock protein 60 (Hsp60) and extra …

Neointimal hyperplasia is a major cause of restenosis after coronary intervention. Because
vascular injury is now recognized to involve an inflammatory response, monocyte …

Objective T-cells are central to the immune response responsible for native atherosclerosis.
The objective of this study is to investigate T-cell contribution to post-interventional …

Scope Akkermansia muciniphila (A. muciniphila) is an intestinal commensal with anti‐
inflammatory properties both in the intestine and other organs. The aim is to investigate the …

Acute and chronic inflammatory disorders are characterized by detrimental cytokine and
chemokine expression. Frequently, the chemotactic activity of cytokines depends on a …

Objective—Annexin A5 (AnxA5) has antithrombotic, antiapoptotic, and antiinflammatory
properties; we investigated its effectiveness against vascular inflammation, remodeling, and …