[HTML][HTML] Biological effects of quinolones: a family of broad-spectrum antimicrobial agents
AR Millanao, AY Mora, NA Villagra, SA Bucarey… - Molecules, 2021 - mdpi.com
Broad antibacterial spectrum, high oral bioavailability and excellent tissue penetration
combined with safety and few, yet rare, unwanted effects, have made the quinolones class of …
combined with safety and few, yet rare, unwanted effects, have made the quinolones class of …
Drug combinations as a first line of defense against coronaviruses and other emerging viruses
The world was unprepared for coronavirus disease 2019 (COVID-19) and remains ill-
equipped for future pandemics. While unprecedented strides have been made developing …
equipped for future pandemics. While unprecedented strides have been made developing …
SARS-CoV-2 and SARS-CoV spike-mediated cell-cell fusion differ in their requirements for receptor expression and proteolytic activation
BF Hörnich, AK Großkopf, S Schlagowski… - Journal of …, 2021 - Am Soc Microbiol
Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) infects cells
through interaction of its spike protein (SARS2-S) with angiotensin-converting enzyme 2 …
through interaction of its spike protein (SARS2-S) with angiotensin-converting enzyme 2 …
[HTML][HTML] Inhibition of acid sphingomyelinase by ambroxol prevents SARS-CoV-2 entry into epithelial cells
A Carpinteiro, B Gripp, M Hoffmann, S Pöhlmann… - Journal of Biological …, 2021 - ASBMB
The acid sphingomyelinase/ceramide system has been shown to be important for cellular
infection with at least some viruses, for instance, rhinovirus or severe acute respiratory …
infection with at least some viruses, for instance, rhinovirus or severe acute respiratory …
In vitro inhibition and molecular docking of a new ciprofloxacin‐chalcone against SARS‐CoV‐2 main protease
R Alaaeldin, M Mustafa… - Fundamental & …, 2022 - Wiley Online Library
Abstract Background/Aim SARS‐CoV‐2 is one of the coronavirus families that emerged at
the end of 2019. It infected the respiratory system and caused a pandemic worldwide …
the end of 2019. It infected the respiratory system and caused a pandemic worldwide …
Ambroxol hydrochloride inhibits the interaction between severe acute respiratory syndrome coronavirus 2 spike protein's receptor binding domain and recombinant …
OA Olaleye, M Kaur, CC Onyenaka - BioRxiv, 2020 - biorxiv.org
Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative
agent of coronavirus disease 2019 (COVID-19), enters the host cells through two main …
agent of coronavirus disease 2019 (COVID-19), enters the host cells through two main …
Advancements in Synthetic Strategies and Biological Effects of Ciprofloxacin Derivatives: A Review
Ciprofloxacin is a widely used antibiotic in the fluoroquinolone class. It is widely
acknowledged by various researchers worldwide, and it has been documented to have a …
acknowledged by various researchers worldwide, and it has been documented to have a …
Effect of the substituted location on luminescent behaviors with Ambroxol moieties: Synthesis, crystal structure and Hirshfeld surface
HR Zhang, JR Zhang, YX Ma, Y Zhou, SX Cheng… - Journal of Molecular …, 2023 - Elsevier
To further exploit the new materials, a set of new salts containing ambroxol and hydroxyl
aromatic carboxylate moieties, namely,[H AXE]+ B–(B= MSA (1), 23A (2) and 26A (3))[AXE …
aromatic carboxylate moieties, namely,[H AXE]+ B–(B= MSA (1), 23A (2) and 26A (3))[AXE …
[HTML][HTML] Ambroxol Treatment Suppresses the Proliferation of Chlamydia pneumoniae in Murine Lungs
Ambroxol (Ax) is used as a mucolytics in the treatment of respiratory tract infections. Ax, at a
general dose for humans, does not alter Chlamydia pneumoniae growth in mice. Therefore …
general dose for humans, does not alter Chlamydia pneumoniae growth in mice. Therefore …
Многообразие эффектов амброксола в терапии острых респираторных инфекций у детей
НА Геппе, МД Шахназарова, СИ Шаталина… - Фарматека, 2022 - elibrary.ru
В статье рассмотрены основные, а также малоизученные эффекты амброксола-
мукоактивного препарата, широко используемого в качестве мукокинетика и …
мукоактивного препарата, широко используемого в качестве мукокинетика и …