The systemic immune response to trauma: an overview of pathophysiology and treatment

JM Lord, MJ Midwinter, YF Chen, A Belli, K Brohi… - The Lancet, 2014 - thelancet.com
Improvements in the control of haemorrhage after trauma have resulted in the survival of
many people who would otherwise have died from the initial loss of blood. However, the …

[HTML][HTML] Shock index as predictor of massive transfusion and mortality in patients with trauma: a systematic review and meta-analysis

A Carsetti, R Antolini, E Casarotta, E Damiani… - Critical Care, 2023 - Springer
Background Management of bleeding trauma patients is still a difficult challenge. Massive
transfusion (MT) requires resources to ensure the safety and timely delivery of blood …

The changing face of major trauma in the UK

A Kehoe, JE Smith, A Edwards, D Yates… - Emergency medicine …, 2015 - emj.bmj.com
Aim Major trauma (MT) has traditionally been viewed as a disease of young men caused by
high-energy transfer mechanisms of injury, which has been reflected in the configuration of …

Development and evaluation of a machine learning model for the early identification of patients at risk for sepsis

RJ Delahanty, JA Alvarez, LM Flynn, RL Sherwin… - Annals of emergency …, 2019 - Elsevier
Study objective The Third International Consensus Definitions (Sepsis-3) Task Force
recommended the use of the quick Sequential [Sepsis-related] Organ Failure Assessment …

Pediatric specific shock index accurately identifies severely injured children

SN Acker, JT Ross, DA Partrick, S Tong… - Journal of pediatric …, 2015 - Elsevier
Introduction Shock index (SI)(heart rate/systolic blood pressure)> 0.9 predicts mortality in
adult trauma patients. We hypothesized that age adjusted SI could more accurately predict …

Wearable sensors to improve detection of patient deterioration

M Joshi, H Ashrafian, L Aufegger, S Khan… - Expert review of …, 2019 - Taylor & Francis
Introduction: Monitoring a patient's vital signs forms a basic component of care, enabling the
identification of deteriorating patients and increasing the likelihood of improving patient …

The compensatory reserve for early and accurate prediction of hemodynamic compromise: a review of the underlying physiology

VA Convertino, MD Wirt, JF Glenn, BC Lein - Shock, 2016 - journals.lww.com
Shock is deadly and unpredictable if it is not recognized and treated in early stages of
hemorrhage. Unfortunately, measurements of standard vital signs that are displayed on …

Development and evaluation of an automated machine learning algorithm for in-hospital mortality risk adjustment among critical care patients

RJ Delahanty, D Kaufman, SS Jones - Critical care medicine, 2018 - journals.lww.com
Objectives: Risk adjustment algorithms for ICU mortality are necessary for measuring and
improving ICU performance. Existing risk adjustment algorithms are not widely adopted. Key …

Major trauma in older persons

B Beck, P Cameron, J Lowthian, M Fitzgerald… - BJS open, 2018 - academic.oup.com
Background Globally, populations are ageing, creating challenges for trauma system
design. Despite this, little is known about causes of injury and long-term outcomes in older …

Validation of the age-adjusted shock index using pediatric trauma quality improvement program data

A Nordin, A Coleman, J Shi, K Wheeler… - Journal of pediatric …, 2018 - jpedsurg.org
Purpose In adults, shock index (SI; heart rate/systolic blood pressure)> 0.9 predicts injury
severity and trauma outcomes. However, age-adjusted shock index (SIPA) out-performs SI …