Although levothyroxine is one of the most prescribed medications in the world, its
bioavailability has been reported to be impaired by many factors, including interfering drugs …

Thyroid hormones play an important role in many metabolic processes in the human body.
However, these processes can often be disrupted by an over or underactivity of the thyroid …

Introduction The tight structure of the blood–brain barrier severely limits the level of drug
therapy for central nervous system disorders. In this study, a novel composite delivery …

Background A microneedle patch loaded with Atractylodes macrocephala Rhizoma water
extract was prepared for the treatment of mammary gland hyperplasia. To explore the …

Bacterial infections are mainly managed by the administration of antibiotics, which are either
cytotoxic or cytostatic to microbes. In some cases, it is inconvenient to treat infections caused …

Hydrogel microneedles represent a promising approach to deliver drug molecules across
skin into systemic circulation in a sustained release manner and without any polymer …

Background: Melanoma is a skin cancer that requires early treatment to prevent metastasis.
In particular, the superficial spreading melanoma, excisional surgery with local …

In recent years, there has been a significant increase in the prevalence of thyroid diseases,
particularly hypothyroidism. In this study, we investigated the impact and mechanisms of …

Аннотация В статье представлен обзор современных подходов и проблем в ведении
пациентов с первичным гипотиреозом. В настоящее время во всем мире проводятся …

Individuals with hypothyroidism will require lifelong thyroxine replacement therapy to
alleviate symptoms and prevent long-term consequences. Levothyroxine (LT4), a synthetic …