Regulation of mammalian mitochondrial dynamics: opportunities and challenges
Mitochondria are highly dynamic organelles and important for a variety of cellular functions.
They constantly undergo fission and fusion events, referred to as mitochondrial dynamics …
They constantly undergo fission and fusion events, referred to as mitochondrial dynamics …
Mitophagy plays a central role in mitochondrial ageing
A Diot, K Morten, J Poulton - Mammalian Genome, 2016 - Springer
The mechanisms underlying ageing have been discussed for decades, and advances in
molecular and cell biology of the last three decades have accelerated research in this area …
molecular and cell biology of the last three decades have accelerated research in this area …
The interplay between respiratory supercomplexes and ROS in aging
ML Genova, G Lenaz - Antioxidants & redox signaling, 2015 - liebertpub.com
Significance: The molecular mechanism of aging is still vigorously debated, although a
general consensus exists that mitochondria are significantly involved in this process …
general consensus exists that mitochondria are significantly involved in this process …
ROCK2 inhibition: A futuristic approach for the management of Alzheimer's disease
Neurons depend on mitochondrial functions for membrane excitability, neurotransmission,
and plasticity. Mitochondrial dynamics are important for neural cell maintenance. To …
and plasticity. Mitochondrial dynamics are important for neural cell maintenance. To …
Simultaneous impairment of mitochondrial fission and fusion reduces mitophagy and shortens replicative lifespan
D Bernhardt, M Müller, AS Reichert, HD Osiewacz - Scientific reports, 2015 - nature.com
Aging of biological systems is accompanied by degeneration of mitochondrial functions.
Different pathways are active to counteract the processes which lead to mitochondrial …
Different pathways are active to counteract the processes which lead to mitochondrial …
Redox regulation in amyotrophic lateral sclerosis
S Parakh, DM Spencer, MA Halloran… - Oxidative medicine …, 2013 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that results from the
death of upper and lower motor neurons. Due to a lack of effective treatment, it is imperative …
death of upper and lower motor neurons. Due to a lack of effective treatment, it is imperative …
Intracellular reactive oxygen species trigger mitochondrial dysfunction and apoptosis in cadmium telluride quantum dots-induced liver damage
Q Liu, D Wu, Y Ma, Y Cao, Y Pang, M Tang, Y Pu… - NanoImpact, 2022 - Elsevier
Quantum dots (QDs), also known as semiconductor QDs, have specific
photoelectricproperties which find application in bioimaging, solar cells, and light-emitting …
photoelectricproperties which find application in bioimaging, solar cells, and light-emitting …
Scolopendin, an antimicrobial peptide from centipede, attenuates mitochondrial functions and triggers apoptosis in Candida albicans
H Lee, JS Hwang, DG Lee - Biochemical Journal, 2017 - portlandpress.com
Centipedes, a type of arthropod, reportedly produce antimicrobial peptides as part of an
innate immune response. Scolopendin (SPSEKAGLQPVGRIGRMLKK) is a novel …
innate immune response. Scolopendin (SPSEKAGLQPVGRIGRMLKK) is a novel …
Programmed cell death initiation and execution in budding yeast
R Strich - Genetics, 2015 - academic.oup.com
Apoptosis or programmed cell death (PCD) was initially described in metazoans as a
genetically controlled process leading to intracellular breakdown and engulfment by a …
genetically controlled process leading to intracellular breakdown and engulfment by a …
Ubiquitin–proteasome-mediated cyclin C degradation promotes cell survival following nitrogen starvation
SD Willis, SE Hanley, T Beishke, PD Tati… - Molecular biology of …, 2020 - Am Soc Cell Biol
Environmental stress elicits well-orchestrated programs that either restore cellular
homeostasis or induce cell death depending on the insult. Nutrient starvation triggers the …
homeostasis or induce cell death depending on the insult. Nutrient starvation triggers the …