Noncoding RNAs as regulators of STAT3 pathway in gastrointestinal cancers: Roles in cancer progression and therapeutic response
M Ashrafizadeh, CD Mohan… - Medicinal research …, 2023 - Wiley Online Library
Gastrointestinal (GI) tumors (cancers of the esophagus, gastric, liver, pancreas, colon, and
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …
Therapeutic potential of extracellular vesicles from diverse sources in cancer treatment
H Lin, J Zhou, T Ding, Y Zhu, L Wang, T Zhong… - European Journal of …, 2024 - Springer
Cancer, a prevalent and complex disease, presents a significant challenge to the medical
community. It is characterized by irregular cell differentiation, excessive proliferation …
community. It is characterized by irregular cell differentiation, excessive proliferation …
[HTML][HTML] Uptake of oxidative stress-mediated extracellular vesicles by vascular endothelial cells under low magnitude shear stress
X Qin, K Zhang, J Qiu, N Wang, K Qu, Y Cui, J Huang… - Bioactive Materials, 2022 - Elsevier
Extracellular vesicles (EVs) are increasingly used as delivery vehicles for drugs and
bioactive molecules, which usually require intravascular administration. The endothelial …
bioactive molecules, which usually require intravascular administration. The endothelial …
MicroRNA interrelated epithelial mesenchymal transition (EMT) in glioblastoma
MicroRNAs (miRNA) are small non-coding RNAs that are 20–23 nucleotides in length,
functioning as regulators of oncogenes or tumor suppressor genes. They are molecular …
functioning as regulators of oncogenes or tumor suppressor genes. They are molecular …
Mesenchymal transformation: the rosetta stone of glioblastoma pathogenesis and therapy resistance
Z Azam, SST TO, BA Tannous - Advanced science, 2020 - Wiley Online Library
Despite decades of research, glioblastoma (GBM) remains invariably fatal among all forms
of cancers. The high level of inter‐and intratumoral heterogeneity along with its biological …
of cancers. The high level of inter‐and intratumoral heterogeneity along with its biological …
[HTML][HTML] PTRF/Cavin-1 enhances chemo-resistance and promotes temozolomide efflux through extracellular vesicles in glioblastoma
E Yang, L Wang, W Jin, X Liu, Q Wang, Y Wu, Y Tan… - Theranostics, 2022 - ncbi.nlm.nih.gov
Background: The concentration and duration of intracellular drugs have always been the key
factors for determining the efficacy of the treatment. Efflux of chemotherapeutic drugs or …
factors for determining the efficacy of the treatment. Efflux of chemotherapeutic drugs or …
Current insights on extracellular vesicle-mediated glioblastoma progression: Implications in drug resistance and epithelial-mesenchymal transition
S Mukherjee, PP Pillai - Biochimica et Biophysica Acta (BBA)-General …, 2022 - Elsevier
Background Glioblastoma multiforme (GBM) is one of the most fatal tumors of the central
nervous system with high rate of disease progression, diagnosis, prognosis and low survival …
nervous system with high rate of disease progression, diagnosis, prognosis and low survival …
Therapy-induced shaping of the glioblastoma microenvironment: Macrophages at play
J Erbani, M Boon, L Akkari - Seminars in Cancer Biology, 2022 - Elsevier
The intricate cross-talks between tumor cells and their microenvironment play a key role in
cancer progression and resistance to treatment. In recent years, targeting pro-tumorigenic …
cancer progression and resistance to treatment. In recent years, targeting pro-tumorigenic …
Role of tumor-derived extracellular vesicles in glioblastoma
Y Chen, Y Jin, N Wu - Cells, 2021 - mdpi.com
Glioblastoma (GBM) is the most common primary central nervous system tumor and one of
the most lethal cancers worldwide, with morbidity of 5.26 per 100,000 population per year …
the most lethal cancers worldwide, with morbidity of 5.26 per 100,000 population per year …
The multifaceted role of extracellular vesicles in glioblastoma: microRNA nanocarriers for disease progression and gene therapy
Glioblastoma (GB) is the most aggressive form of brain cancer in adults, characterized by
poor survival rates and lack of effective therapies. MicroRNAs (miRNAs) are small, non …
poor survival rates and lack of effective therapies. MicroRNAs (miRNAs) are small, non …