[HTML][HTML] Role of the gut microbiota in inflammatory bowel disease pathogenesis: what have we learnt in the past 10 years?
GL Hold, M Smith, C Grange, ER Watt… - World journal of …, 2014 - ncbi.nlm.nih.gov
Our understanding of the microbial involvement in inflammatory bowel disease (IBD)
pathogenesis has increased exponentially over the past decade. The development of newer …
pathogenesis has increased exponentially over the past decade. The development of newer …
Advances and perspectives in in vitro human gut fermentation modeling
AN Payne, A Zihler, C Chassard, C Lacroix - Trends in biotechnology, 2012 - cell.com
The gut microbiota is a highly specialized organ containing host-specific assemblages of
microbes whereby metabolic activity directly impacts human health and disease. In vitro gut …
microbes whereby metabolic activity directly impacts human health and disease. In vitro gut …
Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis
MEV Johansson, JK Gustafsson, J Holmén-Larsson… - Gut, 2014 - gut.bmj.com
Objective The inner mucus layer in mouse colon normally separates bacteria from the
epithelium. Do humans have a similar inner mucus layer and are defects in this mucus layer …
epithelium. Do humans have a similar inner mucus layer and are defects in this mucus layer …
Germ-free and antibiotic-treated mice are highly susceptible to epithelial injury in DSS colitis
C Hernández-Chirlaque, CJ Aranda… - Journal of Crohn's …, 2016 - academic.oup.com
Abstract Background and Aims: Intestinal microbiota is required to maintain immune
homeostasis and intestinal barrier function. At the same time, intraluminal bacteria are …
homeostasis and intestinal barrier function. At the same time, intraluminal bacteria are …
Current and emerging drugs for the treatment of inflammatory bowel disease
JK Triantafillidis, E Merikas… - … design, development and …, 2011 - Taylor & Francis
During the last decade a large number of biological agents against tumor necrosis factor-α
(TNF-α), as well as many biochemical substances and molecules specifically for the medical …
(TNF-α), as well as many biochemical substances and molecules specifically for the medical …
Dysbiosis in intestinal inflammation: cause or consequence
The intestinal microbiota encompasses hundreds of bacterial species that constitute a
relatively stable ecosystem. Alteration in the microbiota composition may arise from …
relatively stable ecosystem. Alteration in the microbiota composition may arise from …
[HTML][HTML] The immunological basis of inflammatory bowel disease
FAR Silva, BL Rodrigues, MLS Ayrizono… - … research and practice, 2016 - hindawi.com
Inflammatory bowel diseases (IBDs) are chronic ailments, Crohn's disease and ulcerative
colitis being the most important. These diseases present an inflammatory profile and they …
colitis being the most important. These diseases present an inflammatory profile and they …
Opportunities and challenges of whole-genome and-exome sequencing
BS Petersen, B Fredrich, MP Hoeppner, D Ellinghaus… - BMC genetics, 2017 - Springer
Recent advances in the development of sequencing technologies provide researchers with
unprecedented possibilities for genetic analyses. In this review, we will discuss the history of …
unprecedented possibilities for genetic analyses. In this review, we will discuss the history of …
Human gut microbiota: toward an ecology of disease
S Selber-Hnatiw, B Rukundo, M Ahmadi… - Frontiers in …, 2017 - frontiersin.org
Composed of trillions of individual microbes, the human gut microbiota has adapted to the
uniquely diverse environments found in the human intestine. Quickly responding to the …
uniquely diverse environments found in the human intestine. Quickly responding to the …
The role of the gut microbiota in the treatment of inflammatory bowel diseases
I Aggeletopoulou, C Konstantakis… - Microbial …, 2019 - Elsevier
The human intestinal microbiota coevolves with its host through a symbiotic relationship and
exerts great influence on substantial functions including aspects of physiology, metabolism …
exerts great influence on substantial functions including aspects of physiology, metabolism …