CD24 is a protein found on the surface of cells that plays a crucial role in the proliferation,
invasion, and spread of cancer cells. It adheres to cell membranes through …

Given its nearly ubiquitous expression on plasma cells and limited expression on essential
normal tissue, the G protein-coupled receptor class C group 5 member D (GPRC5D) …

Anti-multiple myeloma B cell maturation antigen (BCMA)-specific chimeric antigen receptor
(CAR) T-cell therapies represent a promising treatment strategy with high response rates in …

Drug resistance poses a significant challenge in cancer treatment. Despite the initial
effectiveness of therapies such as chemotherapy, targeted therapy and immunotherapy …

For patients with relapsed/refractory multiple myeloma with a relapse after B-cell maturation
antigen (BCMA)–directed chimeric antigen receptor T-cell therapy (CAR-T), optimal salvage …

Drug resistance poses a crucial challenge in healthcare, with response rates to
chemotherapy and targeted therapy remaining low. Individual patient's resistance is …

Cellular immunotherapy, particularly CAR-T cells, has shown potential in the improvement of
outcomes in patients with refractory and recurrent malignancies of the blood. However …

Introduction Current multistep methods utilized for preparing and cryopreserving single-cell
suspensions from blood samples for single-cell RNA sequencing (scRNA-seq) are time …

Background Globally, esophageal squamous cell carcinoma (ESCC) stands out as a
common cancer type, characterized by its notably high rates of occurrence and mortality …

Relapsed/refractory multiple myeloma patients with extramedullary disease (EMD) have
unfavorable prognosis and lack effective therapy. Chimeric antigen receptor (CAR) T‐cell …