Vitamin C (L-ascorbic acid) has been known as an antioxidant for most people. However, its
physiological role is much larger and encompasses very different processes ranging from …

Cellular senescence is an irreversible state of cell cycle arrest occurring in response to
stressful stimuli, such as telomere attrition, DNA damage, reactive oxygen species, and …

Loss-of-function mutations in TET2 occur frequently in patients with clonal hematopoiesis,
myelodysplastic syndrome (MDS), and acute myeloid leukemia (AML) and are associated …

Vitamin C (Vit C) is considered to be a vital antioxidant molecule in the brain. Intracellular Vit
C helps maintain integrity and function of several processes in the central nervous system …

Whether vitamin C (ascorbate) has a role to play as an anti-cancer agent has been debated
for decades. Ascorbate has been used by cancer patients in an unregulated environment …

Growing evidence suggests that vitamin C supplementation may be an effective adjunct
therapy in the management of people with diabetes. This paper critically reviews the current …

The use of intravenous vitamin C (IVC) for cancer therapy has long been an area of intense
controversy. Despite this, high dose IVC has been administered for decades by …

l-Ascorbic acid (ASA), vitamin C, is a ubiquitous carbohydrate-like compound that has an
essential role in a number of cellular processes, such as collagen synthesis, cellular …

Recently, the discovery of biological and clinical properties of mutated isoforms 1 and 2
mutations of isocitrate dehydrogenases (IDH) 1 and 2, affecting approximately 20% of …

This article reviews intravenous vitamin C (IV C) in cancer care and offers a rational
approach to enable medical oncologists and integrative practitioners to safely provide IV C …