Bubbles in microfluidics: An all-purpose tool for micromanipulation
In recent decades, the integration of microfluidic devices and multiple actuation technologies
at the microscale has greatly contributed to the progress of related fields. In particular …
at the microscale has greatly contributed to the progress of related fields. In particular …
[HTML][HTML] Rotational manipulation of single cells and organisms using acoustic waves
The precise rotational manipulation of single cells or organisms is invaluable to many
applications in biology, chemistry, physics and medicine. In this article, we describe an …
applications in biology, chemistry, physics and medicine. In this article, we describe an …
Review of the clinical applications and technological advances of circulating tumor DNA in cancer monitoring
Y Chang, B Tolani, X Nie, X Zhi, M Hu… - Therapeutics and clinical …, 2017 - Taylor & Francis
Circulating cell-free DNA (cfDNA) released by tumor cells, termed ctDNA, closely reflects the
heterogeneity of primary cancers and their metastases. As a noninvasive, real-time …
heterogeneity of primary cancers and their metastases. As a noninvasive, real-time …
Brain-wide 3D imaging of neuronal activity in Caenorhabditis elegans with sculpted light
T Schrödel, R Prevedel, K Aumayr, M Zimmer… - Nature methods, 2013 - nature.com
Recent efforts in neuroscience research have been aimed at obtaining detailed anatomical
neuronal wiring maps as well as information on how neurons in these networks engage in …
neuronal wiring maps as well as information on how neurons in these networks engage in …
[HTML][HTML] Nested neuronal dynamics orchestrate a behavioral hierarchy across timescales
HS Kaplan, OS Thula, N Khoss, M Zimmer - Neuron, 2020 - cell.com
Classical and modern ethological studies suggest that animal behavior is organized
hierarchically across timescales, such that longer-timescale behaviors are composed of …
hierarchically across timescales, such that longer-timescale behaviors are composed of …
A global brain state underlies C. elegans sleep behavior
ALA Nichols, T Eichler, R Latham, M Zimmer - Science, 2017 - science.org
INTRODUCTION Global brain states such as sleep and wakefulness involve
reconfigurations of neural circuit activity across the entire nervous system. Yet it is not …
reconfigurations of neural circuit activity across the entire nervous system. Yet it is not …
[HTML][HTML] A set of hub neurons and non-local connectivity features support global brain dynamics in C. elegans
K Uzel, S Kato, M Zimmer - Current Biology, 2022 - cell.com
The wiring architecture of neuronal networks is assumed to be a strong determinant of their
dynamical computations. An ongoing effort in neuroscience is therefore to generate …
dynamical computations. An ongoing effort in neuroscience is therefore to generate …
[HTML][HTML] Large-scale microfluidics providing high-resolution and high-throughput screening of Caenorhabditis elegans poly-glutamine aggregation model
Next generation drug screening could benefit greatly from in vivo studies, using small animal
models such as Caenorhabditis elegans for hit identification and lead optimization. Current …
models such as Caenorhabditis elegans for hit identification and lead optimization. Current …
Surface acoustic waves enable rotational manipulation of Caenorhabditis elegans
Controllable, precise, and stable rotational manipulation of model organisms is valuable in
many biomedical, bioengineering, and biophysics applications. We present an …
many biomedical, bioengineering, and biophysics applications. We present an …
[HTML][HTML] Acoustofluidic rotational manipulation of cells and organisms using oscillating solid structures
Controllable rotational manipulation enables multi-dimensional imaging and rapid
screening of single cells and model organisms. Current approaches to rotationally …
screening of single cells and model organisms. Current approaches to rotationally …