Bubbles in microfluidics: An all-purpose tool for micromanipulation

Y Li, X Liu, Q Huang, AT Ohta, T Arai - Lab on a Chip, 2021 - pubs.rsc.org
In recent decades, the integration of microfluidic devices and multiple actuation technologies
at the microscale has greatly contributed to the progress of related fields. In particular …

[HTML][HTML] Rotational manipulation of single cells and organisms using acoustic waves

D Ahmed, A Ozcelik, N Bojanala, N Nama… - Nature …, 2016 - nature.com
The precise rotational manipulation of single cells or organisms is invaluable to many
applications in biology, chemistry, physics and medicine. In this article, we describe an …

Review of the clinical applications and technological advances of circulating tumor DNA in cancer monitoring

Y Chang, B Tolani, X Nie, X Zhi, M Hu… - Therapeutics and clinical …, 2017 - Taylor & Francis
Circulating cell-free DNA (cfDNA) released by tumor cells, termed ctDNA, closely reflects the
heterogeneity of primary cancers and their metastases. As a noninvasive, real-time …

Brain-wide 3D imaging of neuronal activity in Caenorhabditis elegans with sculpted light

T Schrödel, R Prevedel, K Aumayr, M Zimmer… - Nature methods, 2013 - nature.com
Recent efforts in neuroscience research have been aimed at obtaining detailed anatomical
neuronal wiring maps as well as information on how neurons in these networks engage in …

[HTML][HTML] Nested neuronal dynamics orchestrate a behavioral hierarchy across timescales

HS Kaplan, OS Thula, N Khoss, M Zimmer - Neuron, 2020 - cell.com
Classical and modern ethological studies suggest that animal behavior is organized
hierarchically across timescales, such that longer-timescale behaviors are composed of …

A global brain state underlies C. elegans sleep behavior

ALA Nichols, T Eichler, R Latham, M Zimmer - Science, 2017 - science.org
INTRODUCTION Global brain states such as sleep and wakefulness involve
reconfigurations of neural circuit activity across the entire nervous system. Yet it is not …

[HTML][HTML] A set of hub neurons and non-local connectivity features support global brain dynamics in C. elegans

K Uzel, S Kato, M Zimmer - Current Biology, 2022 - cell.com
The wiring architecture of neuronal networks is assumed to be a strong determinant of their
dynamical computations. An ongoing effort in neuroscience is therefore to generate …

[HTML][HTML] Large-scale microfluidics providing high-resolution and high-throughput screening of Caenorhabditis elegans poly-glutamine aggregation model

S Mondal, E Hegarty, C Martin, SK Gökce… - Nature …, 2016 - nature.com
Next generation drug screening could benefit greatly from in vivo studies, using small animal
models such as Caenorhabditis elegans for hit identification and lead optimization. Current …

Surface acoustic waves enable rotational manipulation of Caenorhabditis elegans

J Zhang, S Yang, C Chen, JH Hartman, PH Huang… - Lab on a Chip, 2019 - pubs.rsc.org
Controllable, precise, and stable rotational manipulation of model organisms is valuable in
many biomedical, bioengineering, and biophysics applications. We present an …

[HTML][HTML] Acoustofluidic rotational manipulation of cells and organisms using oscillating solid structures

A Ozcelik, N Nama, PH Huang, M Kaynak… - Small (Weinheim an …, 2016 - ncbi.nlm.nih.gov
Controllable rotational manipulation enables multi-dimensional imaging and rapid
screening of single cells and model organisms. Current approaches to rotationally …