Recent advances in the Friedlander reaction

J Marco-Contelles, E Pérez-Mayoral, A Samadi… - Chemical …, 2009 - ACS Publications
The quinoline ring system1-5 is present in a number of natural6 and synthetic products often
endowed with interesting pharmacological or physical properties. 7, 8 Consequently, a …

Friedlӓnder's synthesis of quinolines as a pivotal step in the development of bioactive heterocyclic derivatives in the current era of medicinal chemistry

S Rajendran, K Sivalingam… - Chemical Biology & …, 2022 - Wiley Online Library
In the current scenario of medicinal chemistry, quinoline plays a pivotal role in the design of
new heterocyclic compounds with several pharmacological properties, so the search for new …

Advances in the syntheses of quinoline and quinoline-annulated ring systems

S Madapa, Z Tusi, S Batra - Current Organic Chemistry, 2008 - ingentaconnect.com
Quinoline is a heterocyclic scaffold of paramount importance to human race. The utility of
quinoline derivatives in the areas of medicine, food, catalyst, dye, materials, refineries and …

Friedlander Synthesis of poly-substituted quinolines: a mini review

M Fallah-Mehrjardi - Mini-Reviews in Organic Chemistry, 2017 - ingentaconnect.com
Quinolines and their derivatives are an important class of heterocyclic compounds that occur
widely in natural products, drugs and biologically active compounds. A large variety of …

Organometal-Free Arylation and Arylation/Trifluoroacetylation of Quinolines by Their Reaction with CF3-ynones and Base-Induced Rearrangement

VM Muzalevskiy, KV Belyaeva… - The Journal of …, 2020 - ACS Publications
The reaction of quinolines with CF3-ynones resulted in the formation of 1, 3-
oxazinoquinolines. Subsequent treatment of the reaction mixture with a base initiated deep …

Solvent‐Free Synthesis of New Quinoline Derivatives via Eaton's Reagent Catalysed Friedländer Synthesis

R Satheeshkumar, KJR Prasad, W Wen‐Long… - …, 2022 - Wiley Online Library
An interest for the development of new 2‐acetyl/propanoyl quinolines via Friedländer
synthesis is one of the most studied synthetic approaches. Herein we report the use of a …

Cu-catalyzed tandem reactions of fluorinated alkynes with sulfonyl azides en route to 2-trifluoromethylquinolines

Y Li, L Zhang, L Zhang, Y Wu, Y Gong - Organic & Biomolecular …, 2013 - pubs.rsc.org
Cu-catalyzed tandem reactions of fluorinated alkynes with sulfonyl azides en route to 2-trifluoromethylquinolines
- Organic & Biomolecular Chemistry (RSC Publishing) DOI:10.1039/C3OB41658E Royal …

Poly (N-bromo-N-ethylbenzene-1, 3-disulfonamide) and N, N, N′, N′-tetrabromobenzene-1, 3-disulfonamide as efficient reagents for synthesis of quinolines

R Ghorbani-Vaghei, S Akbari-Dadamahaleh - Tetrahedron Letters, 2009 - Elsevier
Poly (N-bromo-N-ethylbenzene-1, 3-disulfonamide)[PBBS] and N, N, N′, N′-
tetrabromobenzene-1, 3-disulfonamide [TBBDA] were used as efficient reagents for the …

[PDF][PDF] 2-Acetylbenzofurans: Synthesis, reactions and applications

MA Metwally, BF Abdel-Wahab… - Current Organic Chemistry, 2010 - academia.edu
This review deals with synthesis and reactions of 2-acetylbenzofurans. Some of these
reactions have been applied successfully to the synthesis of biologically important …

Rapid and efficient microwave‐assisted Friedländer quinoline synthesis

HV Bailey, MF Mahon, N Vicker, BVL Potter - ChemistryOpen, 2020 - Wiley Online Library
A microwave‐based methodology facilitates reaction of 2‐aminophenylketones with cyclic
ketones to form a quinoline scaffold. Syntheses of amido‐and amino‐linked 17β …