The endothelium is involved in the control of vascular tone and homeostasis. Risk factors for
arteriosclerosis, as well as other conditions have been shown to be associated with a …

Endothelial injury or dysfunction has been proposed to be one of the initiating events of
atherosclerosis and is associated with an apparent decrease in the production of the …

Background Previous studies suggest that vascular endothelial function may be impaired in
essential hypertension. Although muscarinic agonists dilate blood vessels by releasing an …

Vascular endothelial cells play a key role in cardiovascular regulation by producing a
number of potent vasoactive agents, including the vasodilator molecule nitric oxide (NO) and …

Endothelial injury is a central feature of vascular disease induced by cigarette smoking and
may act as a precursor for future atherosclerosis. Using forearm occlusion plethysmography …

Disorders in choline metabolism are related to disease conditions. We developed a stable-
isotope dilution ultra performance liquid chromatography–mass spectrometry (UPLC …

Research on the biochemistry and physiology of l-arginine has remained an attractive area
for scientists over the last 100 years due to its diverse physiological functions in mammals …

OBJECTIVE To test endothelial function in a group of 10 normoalbuminuric and eight
microalbuminuric insulin-dependent diabetes mellitus patients (ages 28±3 [mean±SE] and …

The endothelium regulates vascular tone through the release of vasoactive agents that act
on the underlying vascular smooth muscle. This endothelial function is impaired in certain …

Nitric oxide derived from the vascular endothelium and other cells of the cardiovascular
system has important roles in physiological regulation of blood flow and may have …