Clinical outcomes associated with anti‐obesity medications in real‐world practice: A systematic literature review

NN Ahmad, S Robinson, T Kennedy‐Martin… - Obesity …, 2021 - Wiley Online Library
Anti‐obesity medications (AOMs) are efficacious and well tolerated in randomized controlled
trials, but findings may not be generalizable to routine clinical practice. This systematic …

Weight loss outcomes associated with semaglutide treatment for patients with overweight or obesity

W Ghusn, A De la Rosa, D Sacoto… - JAMA Network …, 2022 - jamanetwork.com
Importance No retrospective cohort study has assessed the effectiveness of semaglutide at
doses used in randomized clinical trials to treat obesity (ie, 1.7 and 2.4 mg). Objective To …

Novel anti-obesity therapies and their different effects and safety profiles: a critical overview

O Telci Caklili, M Cesur, DP Mikhailidis… - … Syndrome and Obesity, 2023 - Taylor & Francis
Obesity has become an epidemic and a worldwide problem and its treatment is ever-
evolving. Apart from diet and exercise, medication and surgery are other options. After …

Liraglutide 3.0 mg for the management of insufficient weight loss or excessive weight regain post‐bariatric surgery

S Wharton, JL Kuk, M Luszczynski, E Kamran… - Clinical …, 2019 - Wiley Online Library
To assess the effectiveness of liraglutide 3.0 mg in post‐bariatric surgery patients, and to
determine whether this would differ based on the type of bariatric surgery. One hundred …

Effectiveness and tolerability of orlistat and liraglutide in patients with obesity in a real‐world setting: The XENSOR Study

JJ Gorgojo‐Martínez… - … Journal of Clinical …, 2019 - Wiley Online Library
Aims To evaluate in a real‐world setting the effectiveness of two drugs, orlistat and
liraglutide, in patients with overweight or obesity and insufficient weight loss (WL) after a …

Effectiveness of anti-obesity medications approved for long-term use in a multidisciplinary weight management program: a multi-center clinical experience

G Calderon, D Gonzalez-Izundegui, KL Shan… - International Journal of …, 2022 - nature.com
Background and aims Randomized clinical trials have proven the efficacy and safety of Food
and Drug Administration (FDA) approved anti-obesity medications (AOMs) for long-term use …

[PDF][PDF] Clinical effectiveness of semaglutide on weight loss, body composition, and muscle strength in Chinese adults.

J Xiang, XY Ding, W Zhang, J Zhang… - European Review for …, 2023 - europeanreview.org
OBJECTIVE: The aim of this study was to investigate the clinical effectiveness of
semaglutide on weight loss, body composition and muscle strength in the Chinese …

Efficacy and safety of liraglutide for obesity and people who are overweight: a systematic review and meta-analysis of randomized controlled trials

Q Lin, Y Xue, H Zou, Z Ruan, COL Ung… - Expert Review of …, 2022 - Taylor & Francis
Background As the pandemic of obesity presents an increasing serious health challenge
worldwide, additional medical interventions, especially pharmacotherapy, should be …

[HTML][HTML] Estimating and reporting treatment effects in clinical trials for weight management: using estimands to interpret effects of intercurrent events and missing data

S Wharton, A Astrup, L Endahl, MEJ Lean… - International Journal of …, 2021 - nature.com
In the approval process for new weight management therapies, regulators typically require
estimates of effect size. Usually, as with other drug evaluations, the placebo-adjusted …

[HTML][HTML] Liraglutide for weight management in the real world: significant weight loss even if the maximal daily dose is not achieved

L Trenson, S Trenson, F van Nes, C Moyson, M Lannoo… - Obesity Facts, 2022 - karger.com
Introduction: Obesity is a global health challenge, and pharmacologic options are emerging.
Once daily subcutaneous administration of 3 mg liraglutide, a glucagon like peptide-1 …