Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers

P Peluso, B Chankvetadze - Chemical Reviews, 2022 - ACS Publications
It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …

[HTML][HTML] Recent developments in the high-throughput separation of biologically active chiral compounds via high performance liquid chromatography

C De Luca, S Felletti, FA Franchina, D Bozza… - … of Pharmaceutical and …, 2024 - Elsevier
Bioactive compounds, including active pharmaceutical ingredients (APIs), are often chiral
molecules where stereoisomers have different biological and therapeutic activity …

Understanding the transition from high-selective to high-efficient chiral separations by changing the organic modifier with zwitterionic-teicoplanin chiral stationary …

S Felletti, C De Luca, G Mazzoccanti… - Analytical …, 2023 - ACS Publications
The retention behavior of small molecules and N-protected amino acids on a zwitterionic
teicoplanin chiral stationary phase (CSP), prepared on superficially porous particles (SPPs) …

The molecular bases of chiral recognition in 2-(benzylsulfinyl) benzamide enantioseparation

P Peluso, B Chankvetadze - Analytica Chimica Acta, 2021 - Elsevier
Liquid-phase chromatography on chiral stationary phase is still the most popular and
versatile technique to separate enantiomers, which is based on the ability of a chiral selector …

Investigation of retention behavior of natural cannabinoids on differently substituted polysaccharide-based chiral stationary phases under reversed-phase liquid …

C De Luca, A Buratti, W Umstead, P Franco… - … of Chromatography A, 2022 - Elsevier
The growing popularity of cannabis products and recent legalization of cannabis for
recreational purposes have contributed to the increase of the demand for analytical methods …

An examination of the effects of water on normal phase enantioseparations

S Aslani, MF Wahab, ME Kenari, A Berthod… - Analytica Chimica …, 2022 - Elsevier
Superficially porous silica bonded with macrocyclic glycopeptides can separate enantiomers
in various chromatographic formats, including normal phase liquid chromatography (NPLC) …

Investigating the effect of polarity of stationary and mobile phases on retention of cannabinoids in normal phase liquid chromatography

C De Luca, A Buratti, Y Krauke, S Stephan… - Analytical and …, 2022 - Springer
This work reports about a screening of four adsorbents with different polarity employed for
the separation of the main phytocannabinoids contained in Cannabis sativa L., under …

[HTML][HTML] Enantioseparation of a-substituted proline analogs with macrocyclic glycopeptide-based chiral stationary phases immobilized on superficially porous particles …

D Tanács, R Berkecz, DW Armstrong, A Péter… - … of Chromatography A, 2023 - Elsevier
In this study, the liquid chromatography-based direct enantioseparation of the stereoisomers
of α-substituted proline analogs has been investigated utilizing chiral stationary phases with …

Mass transfer kinetics on modern Whelk-O1 chiral stationary phases made on fully-and superficially-porous particles

S Felletti, M Catani, G Mazzoccanti, C De Luca… - … of Chromatography A, 2021 - Elsevier
In this work, a detailed study of mass transfer properties of trans-stilbene oxide (TSO)
enantiomers on two Whelk-O1 chiral stationary phases (CSPs) has been performed. The …

Review of recent insights in the measurement and modelling of the B-term dispersion and related mass transfer properties in liquid chromatography

G Desmet, K Broeckhoven, S Deridder… - Analytica Chimica Acta, 2022 - Elsevier
In this contribution, we review the recent literature relating to the measurement and
modelling of all diffusion-dominated processes contributing to the efficiency of a …