Advances in mass spectrometry (MS) and data processing have led to discoveries in
regulation of cellular metabolism by using metabolomics and lipidomics approaches. 1, 2 …

Lipids are vital biological molecules and play multiple roles in cellular function of
mammalian organisms such as cellular membrane anchoring, signal transduction, material …

Ferroptosis is form of regulated nonapoptotic cell death that is involved in diverse disease
contexts. Small molecules that inhibit glutathione peroxidase 4 (GPX4), a phospholipid …

Accurate quantitative analysis of endogenous analytes is essential for several clinical and
non-clinical applications. LC–MS/MS is the technique of choice for quantitative analyses …

Myocardial ischemia-reperfusion (MIR) injury is a major cause of adverse outcomes of
revascularization after myocardial infarction. To identify the fundamental regulator of …

Neurons in the mature human central nervous system (CNS) perform a wide range of motor,
sensory, regulatory, behavioral, and cognitive functions. Such diverse functional output …

Over the past decade, the number of known eicosanoids has expanded immensely and we
have now developed an ultra-performance liquid chromatography–electrospray ionization …

Globally, cardiovascular diseases (CVDs) are the number one cause of mortality.
Approximately 18 million people died from CVDs in 2015, representing more than 30% of all …

Oxidation of polyunsaturated fatty acids (PUFA) through enzymatic or non-enzymatic free
radical-mediated reactions can yield an array of lipid metabolites including eicosanoids …

Jujube has become a popular food because of its abundant nutritional elements, but its main
consumption in dried form exhibits challenging industrial processing. In current study, the …