Autoimmune diseases (ADs) represent a heterogenous group of complex diseases with
increasing incidence in Western countries and are a major cause of morbidity …

The introduction of targeted biologic therapies has changed the treatment landscape for
autoimmune diseases (ADs) substantially, but although these therapies provide more …

Genomic medicine enables the identification of patients with rare or ultra-rare monogenic
forms of inflammatory bowel disease (IBD) and supports clinical decision making. Patients …

Inflammatory bowel disease is a chronic disease with variable degrees of extent, severity,
and activity. A proportion of patients will have disease that is refractory to licensed therapies …

Background A previous controlled trial of autologous haematopoietic stem-cell
transplantation (HSCT) in patients with refractory Crohn's disease did not meet its primary …

The management of moderate‐to‐severe psoriasis has been transformed by the introduction
of biological therapies. These medicines, particularly those targeting interleukin (IL)‐17 and …

Management of refractory inflammatory bowel disease : Current Opinion in
Gastroenterology Management of refractory inflammatory bowel disease : Current Opinion …

Autoimmune diseases are an important field for the development of bone marrow
transplantation, or hematopoietic stem cell transplantation. In Europe alone, almost 3000 …

In recent years, cell-based therapies have been explored in various immune-mediated
inflammatory diseases, including inflammatory bowel disease (IBD). Cell therapy is the …

Introduction. Postoperative recurrence after surgery for Crohn's disease (CD) is virtually
inevitable, and its mechanism is poorly known. Aim. To review the numerous factors …