A guide to chemokines and their receptors
CE Hughes, RJB Nibbs - The FEBS journal, 2018 - Wiley Online Library
The chemokines (or chemotactic cytokines) are a large family of small, secreted proteins that
signal through cell surface G protein‐coupled heptahelical chemokine receptors. They are …
signal through cell surface G protein‐coupled heptahelical chemokine receptors. They are …
The role of the CXCL12/CXCR4/CXCR7 chemokine axis in cancer
Chemokines are a family of small, secreted cytokines which regulate a variety of cell
functions. The CXC motif chemokine ligand 12 (CXCL12) binds to CXC chemokine receptor …
functions. The CXC motif chemokine ligand 12 (CXCL12) binds to CXC chemokine receptor …
Macrophage migration inhibitory factor (MIF): a multifaceted cytokine regulated by genetic and physiological strategies
K Sumaiya, D Langford, K Natarajaseenivasan… - Pharmacology & …, 2022 - Elsevier
Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine encoded within a
functionally polymorphic genetic locus. MIF was initially recognized as a cytokine generated …
functionally polymorphic genetic locus. MIF was initially recognized as a cytokine generated …
Immunological mechanisms and therapeutic targets of fatty liver diseases
Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are the two major
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …
Inflammatory chemokines in atherosclerosis
Atherosclerosis is a long-term, chronic inflammatory disease of the vessel wall leading to the
formation of occlusive or rupture-prone lesions in large arteries. Complications of …
formation of occlusive or rupture-prone lesions in large arteries. Complications of …
The chemokine system in innate immunity
CL Sokol, AD Luster - Cold Spring Harbor perspectives …, 2015 - cshperspectives.cshlp.org
Chemokines are chemotactic cytokines that control the migration and positioning of immune
cells in tissues and are critical for the function of the innate immune system. Chemokines …
cells in tissues and are critical for the function of the innate immune system. Chemokines …
Inflammatory cytokines in the pathogenesis of cardiovascular disease and cancer
Inflammatory cytokines are highly inducible small glycoproteins or regulatory proteins of low
molecular weight secreted by different cell types. They regulate intercellular communication …
molecular weight secreted by different cell types. They regulate intercellular communication …
Chemokines and chemokine receptors: positioning cells for host defense and immunity
JW Griffith, CL Sokol, AD Luster - Annual review of immunology, 2014 - annualreviews.org
Chemokines are chemo tactic cyto kines that control the migratory patterns and positioning
of all immune cells. Although chemokines were initially appreciated as important mediators …
of all immune cells. Although chemokines were initially appreciated as important mediators …
Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension
This review summarizes an expanding body of knowledge indicating that failure to resolve
inflammation and altered immune processes underlie the development of pulmonary arterial …
inflammation and altered immune processes underlie the development of pulmonary arterial …
[HTML][HTML] Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets
Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for most
deaths in westernized societies with numbers increasing at a marked rate in developing …
deaths in westernized societies with numbers increasing at a marked rate in developing …