Therapeutic targets of oxidative/nitrosative stress and neuroinflammation in ischemic stroke: Applications for natural product efficacy with omics and systemic biology
Oxidative/nitrosative stress and neuroinflammation are critical pathological processes in
cerebral ischemia-reperfusion injury, and their intimate interactions mediate neuronal …
cerebral ischemia-reperfusion injury, and their intimate interactions mediate neuronal …
[HTML][HTML] The effects of baicalin and baicalein on cerebral ischemia: a review
W Liang, X Huang, W Chen - Aging and disease, 2017 - ncbi.nlm.nih.gov
Ischemic stroke, producing a high mortality and morbidity rate, is a common clinical disease.
Enhancing the prevention and control of ischemic stroke is particularly important. Baicalin …
Enhancing the prevention and control of ischemic stroke is particularly important. Baicalin …
NSCs migration promoted and drug delivered exosomes‐collagen scaffold via a bio‐specific peptide for one‐step spinal cord injury repair
L Zhang, C Fan, W Hao, Y Zhuang, X Liu… - Advanced …, 2021 - Wiley Online Library
Spinal cord injury (SCI) is plaguing medical professionals globally due to the complexity of
injury progression. Based on tissue engineering technology, there recently emerges a …
injury progression. Based on tissue engineering technology, there recently emerges a …
[HTML][HTML] The neuroprotective effect of traditional Chinese medicinal plants—A critical review
J Moreira, M Machado, M Dias-Teixeira… - … Pharmaceutica Sinica B, 2023 - Elsevier
Neurodegenerative and neuropsychiatric diseases are increasingly affecting individuals'
quality of life, thus increasing their cost to social and health systems. These diseases have …
quality of life, thus increasing their cost to social and health systems. These diseases have …
Neuroprotective and cognitive enhancement potentials of baicalin: a review
Neurodegenerative diseases are a heterogeneous group of disorders that are characterized
by the gradual loss of neurons. The development of effective neuroprotective agents to …
by the gradual loss of neurons. The development of effective neuroprotective agents to …
Recent advancements in chromone as a privileged scaffold towards the development of small molecules for neurodegenerative therapeutics
Neurodegenerative disorders, ie, Alzheimer's or Parkinson's disease, involve progressive
degeneration of the central nervous system, resulting in memory loss and cognitive …
degeneration of the central nervous system, resulting in memory loss and cognitive …
Targeting RNS/caveolin-1/MMP signaling cascades to protect against cerebral ischemia-reperfusion injuries: potential application for drug discovery
Reactive nitrogen species (RNS) play important roles in mediating cerebral ischemia-
reperfusion injury. RNS activate multiple signaling pathways and participate in different …
reperfusion injury. RNS activate multiple signaling pathways and participate in different …
Baicalin and ginsenoside Rb1 promote the proliferation and differentiation of neural stem cells in Alzheimer's disease model rats
J Zhao, S Lu, H Yu, S Duan, J Zhao - Brain research, 2018 - Elsevier
Background This study aimed to explore the effects of ginsenoside Rb1 and baicalin on the
proliferation and differentiation of neural stem cells (NSC) in Alzheimer's disease model rats …
proliferation and differentiation of neural stem cells (NSC) in Alzheimer's disease model rats …
The potential of plant extracts in cell therapy
C Li, Z Cui, S Deng, P Chen, X Li, H Yang - Stem Cell Research & Therapy, 2022 - Springer
Cell therapy is the frontier technology of biotechnology innovation and the most promising
method for the treatment of refractory diseases such as tumours. However, cell therapy has …
method for the treatment of refractory diseases such as tumours. However, cell therapy has …
Baicalin ameliorates chronic unpredictable mild stress-induced depressive behavior: Involving the inhibition of NLRP3 inflammasome activation in rat prefrontal cortex
X Liu, C Liu - International immunopharmacology, 2017 - Elsevier
Abnormal activation of nucleotide-binding domain, leucine-rich repeat, pyrin domain
containing protein 3 (NLRP3) inflammasome could induce inflammation in the central …
containing protein 3 (NLRP3) inflammasome could induce inflammation in the central …