Adverse drug reactions (ADRs) are a major public health concern and cause significant
patient morbidity and mortality. Pharmacogenomics is the study of how genetic …

Predicting individual risk of chemotherapy-induced severe adverse reaction is a critical
issue when selecting the best treatment for cancer patients. SNPs have been identified in …

Purpose: Paclitaxel is used worldwide in the treatment of breast, lung, ovarian, and other
cancers. Sensory peripheral neuropathy is an associated adverse effect that cannot be …

In recent decades, survival rates in colorectal cancer have improved greatly due to
pharmacological treatment. However, many patients end up developing adverse drug …

Background Breast cancer is a global problem, and a large number of new cases are
diagnosed every year. Capecitabine is effective in patients with metastatic breast cancer …

BACKGROUND Palmar‐plantar erythrodysesthesia syndrome (PPES) is an uncommon side
effect of high‐dose cytarabine or methotrexate. Prior case reports of PPES have been …

Purpose Capecitabine is important in breast cancer treatment but causes diarrhea and hand-
foot syndrome (HFS), affecting adherence and quality of life. We sought to identify …

Fluoropyrimidines, including 5-fluororacil (5FU) and its pro-drug Capecitabine, are the
common treatment for colorectal, breast, neck and head cancers—either as monotherapy or …

We describe an unusual case of subacute cutaneous lupus erythematosus concurrent with
hand‐foot syndrome, apparently associated with capecitabine treatment. We hypothesise …

Colorectal cancer (CRC) is often linked to adverse drug reactions (ADRs), which can be
severe or even fatal. To address this issue, pharmacogenetic studies have emerged to help …