Identification and prioritization of environmental organic pollutants: from an analytical and toxicological perspective

T Ruan, P Li, H Wang, T Li, G Jiang - Chemical Reviews, 2023 - ACS Publications
Exposure to environmental organic pollutants has triggered significant ecological impacts
and adverse health outcomes, which have been received substantial and increasing …

Untangling the chemical complexity of plastics to improve life cycle outcomes

KL Law, MJ Sobkowicz, MP Shaver… - Nature Reviews Materials, 2024 - nature.com
A diversity of chemicals are intentionally added to plastics to enhance their properties and
aid in manufacture. Yet the accumulated chemical composition of these materials is …

Pervasive exposure of wild small mammals to legacy and currently used pesticide mixtures in arable landscapes

C Fritsch, B Appenzeller, L Burkart, M Coeurdassier… - Scientific Reports, 2022 - nature.com
Abstract Knowledge gaps regarding the potential role of pesticides in the loss of agricultural
biodiversity worldwide and mixture-related issues hamper proper risk assessment of …

[HTML][HTML] Indication of the impact of environmental stress on the responses of the bivalve mollusk Unio tumidus to ibuprofen and microplastics based on biomarkers of …

V Martyniuk, V Khoma, T Matskiv, V Baranovsky… - … and Physiology Part C …, 2022 - Elsevier
The vulnerability of bivalve mollusks to micropollutants is estimated mainly in single model
exposures. However, chronic environmental stress and complex exposures can modulate …

The exposome and toxicology: a win–win collaboration

R Barouki, K Audouze, C Becker, L Blaha… - Toxicological …, 2022 - academic.oup.com
The development of the exposome concept has been one of the hallmarks of environmental
and health research for the last decade. The exposome encompasses the life course …

Two-compartmental toxicokinetic model predicts interspecies sensitivity variation of imidacloprid to aquatic invertebrates

H Su, Q Zhang, K Huang, WX Wang, H Li… - Environmental …, 2023 - ACS Publications
Interspecies sensitivity to the same chemical can be several orders of magnitude different.
Quantifying toxicologically internal levels and toxicokinetic (TK) parameters is critical in …

Merging the exposome into an integrated framework for “omics” sciences

EJ Price, CM Vitale, GW Miller, A David, R Barouki… - IScience, 2022 - cell.com
The exposome concept encourages holistic consideration of the non-genetic factors
(environmental exposures including lifestyle) that influence an individual's health over their …

Stress responses of bivalve mollusc Unio tumidus from two areas to ibuprofen, microplastic and their mixture

V Martyniuk, B Gylytė, T Matskiv, V Khoma, H Tulaidan… - Ecotoxicology, 2022 - Springer
Even though bivalve molluscs are recognized as bioindicators of freshwater quality, their
responses to multiple stressors are unpredictable. This study aims to elucidate the inter …

Charting the landscape of the environmental exposome

X Wei, Z Huang, L Jiang, Y Li, X Zhang, Y Leng… - IMeta, 2022 - Wiley Online Library
The exposome depicts the total exposures in the lifetime of an organism. Human exposome
comprises exposures from environmental and humanistic sources. Biological, chemical, and …

The effect of environment on depressive symptoms in late adolescence and early adulthood: an exposome-wide association study and twin modeling

Z Wang, S Zellers, AM Whipp… - Nature Mental …, 2023 - nature.com
The exposome represents the totality of environmental effects, but systematic evaluation
between it and depressive symptoms is scant. Here we sought to comprehensively identify …