Antimicrobial peptides: from design to clinical application

C Zhang, M Yang - Antibiotics, 2022 - mdpi.com
Infection of multidrug-resistant (MDR) bacteria, such as methicillin-resistant Staphylococcus
aureus (MRSA), carbapenem-resistant Enterobacteriaceae (CRE), and extended-spectrum …

Cefiderocol, a siderophore cephalosporin, as a treatment option for infections caused by carbapenem-resistant Enterobacterales

KS Kaye, T Naas, JM Pogue, GM Rossolini - Infectious Diseases and …, 2023 - Springer
Carbapenem-resistant Enterobacterales (CRE) remain a significant public health threat,
and, despite recent approvals, new antibiotics are needed. Severe infections caused by …

Antibiotics and bacterial resistance—a short story of an endless arms race

A Baran, A Kwiatkowska, L Potocki - International Journal of Molecular …, 2023 - mdpi.com
Despite the undisputed development of medicine, antibiotics still serve as first-choice drugs
for patients with infectious disorders. The widespread use of antibiotics results from a wide …

Antibacterial mechanisms of zinc oxide nanoparticle against bacterial food pathogens resistant to beta-lactam antibiotics

R Krishnamoorthy, J Athinarayanan, VS Periyasamy… - Molecules, 2022 - mdpi.com
The increase in β-lactam-resistant Gram-negative bacteria is a severe recurrent problem in
the food industry for both producers and consumers. The development of nanotechnology …

β-Lactam potentiators to re-sensitize resistant pathogens: Discovery, development, clinical use and the way forward

L Narendrakumar, M Chakraborty, S Kumari… - Frontiers in …, 2023 - frontiersin.org
β-lactam antibiotics are one of the most widely used and diverse classes of antimicrobial
agents for treating both Gram-negative and Gram-positive bacterial infections. The β-lactam …

Klebsiella pneumoniae clinical isolates with features of both multidrug-resistance and hypervirulence have unexpectedly low virulence

TJ Kochan, SH Nozick, A Valdes, SD Mitra… - Nature …, 2023 - nature.com
Klebsiella pneumoniae has been classified into two types, classical K. pneumoniae (cKP)
and hypervirulent K. pneumoniae (hvKP). cKP isolates are highly diverse and important …

Overview of antimicrobial resistance: an emerging silent pandemic

M Paneri, P Sevta - Global Journal of Medical, Pharmaceutical, and …, 2023 - gjmpbu.org
Before the outbreak of Coronavirus disease-19, one of the top 10 most risks identified by the
World Health Organization (WHO) is antimicrobial resistance (AMR) that is also known as …

Impact of short chain fatty acids (SCFAs) on antimicrobial activity of new β-lactam/β-lactamase inhibitor combinations and on virulence of Escherichia coli isolates

AA Kadry, MA El-Antrawy, AM El-Ganiny - The Journal of Antibiotics, 2023 - nature.com
In a healthy gut microbiota, short chain fatty acids (SCFAs) are produced. The antibacterial
action of SCFAs against intestinal pathogens makes them useful for ensuring the safety of …

[PDF][PDF] Antimicrobial mechanisms of traditional Chinese medicine and reversal of drug resistance: a narrative review.

BG Liu, M Xie, Y Dong, H Wu, DD He… - European Review for …, 2022 - europeanreview.org
OBJECTIVE: In recent years, the extensive use of antibiotics worldwide has led to an
increase in the number of drug-resistant bacterial strains, thus resulting in an increasingly …

Prevalence and molecular characterization of ESBL-producing Enterobacteriaceae in Egypt: a systematic review and meta-analysis of hospital and community …

A Azzam, H Khaled, D Samer, WM Nageeb - Antimicrobial Resistance & …, 2024 - Springer
ESBL-producing Enterobacteriaceae (ESBL-PE) represent a significant global health threat.
In response to this growing concern and the lack of a surveillance system for ESBL-PE …