Structure–function relationships in protein homorepeats

CA Elena-Real, P Mier, N Sibille… - Current Opinion in …, 2023 - Elsevier
Homorepeats (or polyX), protein segments containing repetitions of the same amino acid,
are abundant in proteomes from all kingdoms of life and are involved in crucial biological …

[HTML][HTML] The structural plasticity of polyglutamine repeats

PJB Pereira, JA Manso, S Macedo-Ribeiro - Current Opinion in Structural …, 2023 - Elsevier
From yeast to humans, polyglutamine (polyQ) repeat tracts are found frequently in the
proteome and are particularly prominent in the activation domains of transcription factors …

Enzyme-based electrochemical biosensor for antimonite detection in water

R Pei, L Ye, C Jing - Biosensors and Bioelectronics, 2023 - Elsevier
Antimonite (Sb III) is a naturally occurring contaminant demanding on-site ultrasensitive
detection. The enzyme-based electrochemical (EC) biosensors are promising, but the lack of …

Polyglutamine disease proteins: Commonalities and differences in interaction profiles and pathological effects

M Bonsor, O Ammar, S Schnoegl, EE Wanker… - …, 2024 - Wiley Online Library
Currently, nine polyglutamine (polyQ) expansion diseases are known. They include
spinocerebellar ataxias (SCA1, 2, 3, 6, 7, 17), spinal and bulbar muscular atrophy (SBMA) …

Reviewing the Structure–Function Paradigm in Polyglutamine Disorders: A Synergistic Perspective on Theoretical and Experimental Approaches

NS Moldovean-Cioroianu - International Journal of Molecular Sciences, 2024 - mdpi.com
Polyglutamine (polyQ) disorders are a group of neurodegenerative diseases characterized
by the excessive expansion of CAG (cytosine, adenine, guanine) repeats within host …