The nervous system governs both ontogeny and oncology. Regulating organogenesis
during development, maintaining homeostasis, and promoting plasticity throughout life, the …

Immunotherapies have shown benefits across a range of human cancers, but not pancreatic
ductal adenocarcinoma (PDAC). Recent evidence suggests that the immunosuppressive …

Although nutrient-starvation therapies can elicit strong anti-tumor effects in multiple
carcinomas, it has been convincingly demonstrated that cancer cells exploit the tumor …

The biological and pathological importance of mutual interactions between the nervous
system and cancer have become increasingly evident. The emerging field of cancer …

Electroreduction of carbon dioxide (CO 2) into high value-added fuels and chemicals with
excellent efficiency is an attractive but challenging route to alleviate energy crisis and …

Cancer neuroscience has emerged as a burgeoning field for the investigation of cancer-
nervous system interactions. Perineural invasion (PNI) is defined as the presence of cancer …

Head and neck squamous cell carcinoma are highly innervated by peripheral sensory
neurons. Local neurotransmitter release (eg, calcitonin gene‐related peptide (CGRP)) from …

Background Noninvasive detection of early stage cancers with accurate prediction of tumor
tissue-of-origin could improve patient prognosis. Because miRNA profiles differ between …

Recent evidence demonstrates that colon cancer stem cells (CSCs) can generate neurons
that synapse with tumor innervating fibers required for tumorigenesis and disease …

Although the pathogenic operations of cancer–nerve crosstalk (eg, neuritogenesis,
neoneurogensis, and perineural invasion—PNI) in the peripheral nervous system (PNS) …