Background As a result of widespread chloroquine and sulphadoxine-pyrimethamine (SP)
resistance, 90% of sub-Saharan African countries had adopted policies of artemisinin-based …

Multiplicity of infection (MOI), also termed complexity of infection (COI), is defined as the
number of genetically distinct parasite strains co-infecting a single host, which is an …

Land use changes have been suggested as one of the causes for malaria epidemics in the
African highlands. This study investigated the effects of deforestation-induced changes in …

Background The efficacy of anti-malarial drugs is assessed over a period of 28-63 days
(depending on the drugs' residence time) following initiation of treatment in order to capture …

Apicomplexan parasites include many parasites of importance either for livestock or as
causative agents of human diseases. The importance of these parasites has been …

Multiplicity of infection (MOI) and genetic diversity of P. falciparum infections are important
surrogate indicators for assessing malaria transmission intensity in different regions of …

Background Malaria parasite population genetic structure varies among areas of differing
endemicity, but this has not been systematically studied across Plasmodium falciparum …

At a time when effective tools for monitoring malaria control and eradication efforts are
crucial, the increasing availability of molecular data motivates their application to …

Background Parasite genetic diversity and multiplicity of infection (MOI) affect clinical
outcomes, response to drug treatment and naturally-acquired or vaccine-induced immunity …

Background A commonly used measure of malaria transmission intensity is the
entomological inoculation rate (EIR), defined as the product of the human biting rate (HBR) …