[HTML][HTML] Three pillars of automated home-cage phenotyping of mice: novel findings, refinement, and reproducibility based on literature and experience

V Voikar, S Gaburro - Frontiers in behavioral neuroscience, 2020 - frontiersin.org
Animal models of neurodegenerative and neuropsychiatric disorders require extensive
behavioral phenotyping. Currently, this presents several caveats and the most important …

[HTML][HTML] EEG analytics for early detection of autism spectrum disorder: a data-driven approach

WJ Bosl, H Tager-Flusberg, CA Nelson - Scientific reports, 2018 - nature.com
Autism spectrum disorder (ASD) is a complex and heterogeneous disorder, diagnosed on
the basis of behavioral symptoms during the second year of life or later. Finding scalable …

Traditional Chinese medicine: potential approaches from modern dynamical complexity theories

Y Ma, K Zhou, J Fan, S Sun - Frontiers of medicine, 2016 - Springer
Despite the widespread use of traditional Chinese medicine (TCM) in clinical settings,
proving its effectiveness via scientific trials is still a challenge. TCM views the human body …

[HTML][HTML] Extracellular ATP drives systemic inflammation, tissue damage and mortality

A Cauwels, E Rogge, B Vandendriessche… - Cell death & …, 2014 - nature.com
Systemic inflammatory response syndromes (SIRS) may be caused by both infectious and
sterile insults, such as trauma, ischemia-reperfusion or burns. They are characterized by …

[HTML][HTML] Heart rate variability as a Translational dynamic biomarker of altered autonomic function in Health and Psychiatric disease

A Agorastos, AC Mansueto, T Hager, E Pappi… - Biomedicines, 2023 - mdpi.com
The autonomic nervous system (ANS) is responsible for the precise regulation of tissue
functions and organs and, thus, is crucial for optimal stress reactivity, adaptive responses …

Beat-to-beat blood pressure variability: an early predictor of disease and cardiovascular risk

NMZ Bakkar, AF El-Yazbi, FA Zouein… - Journal of …, 2021 - journals.lww.com
Blood pressure (BP) varies on the long, short and very-short term. Owing to the hidden
physiological and pathological information present in BP time-series, increasing interest has …

Multiscale entropy analysis of heart rate variability in heart failure, hypertensive, and sinoaortic-denervated rats: classical and refined approaches

LEV Silva, RM Lataro, JA Castania… - American Journal …, 2016 - journals.physiology.org
The analysis of heart rate variability (HRV) by nonlinear methods has been gaining
increasing interest due to their ability to quantify the complexity of cardiovascular regulation …

Multidimensional and fuzzy sample entropy (SampEnMF) for quantifying H&E histological images of colorectal cancer

LFS Dos Santos, LA Neves, GB Rozendo… - Computers in biology …, 2018 - Elsevier
In this study, we propose to use a method based on the combination of sample entropy with
multiscale and multidimensional approaches, along with a fuzzy function. The model was …

Assessing multiscale complexity of short heart rate variability series through a model-based linear approach

A Porta, V Bari, G Ranuzzi, B De Maria… - … Journal of Nonlinear …, 2017 - pubs.aip.org
We propose a multiscale complexity (MSC) method assessing irregularity in assigned
frequency bands and being appropriate for analyzing the short time series. It is grounded on …

[HTML][HTML] Information-domain analysis of cardiovascular complexity: Night and day modulations of entropy and the effects of hypertension

P Castiglioni, G Parati, A Faini - Entropy, 2019 - mdpi.com
Multiscale entropy (MSE) provides information-domain measures of the systems' complexity.
The increasing interest in MSE of the cardiovascular system lies in the possibility of …