The eye contains a complex network of physiological information and biomarkers for
monitoring disease and managing health, and ocular devices can be used to effectively …

Abstract Parkinson's disease (PD), the second most common progressive
neurodegenerative disease, develops and progresses for 10–15 years before the clinical …

Increasing evidence suggests that alpha-synuclein (α-syn) oligomers are obligate
intermediates in the pathway involved in α-syn fibrillization and Lewy body (LB) formation …

Over the past decade, non-invasive wearable chemical sensors have gained tremendous
attention in the field of personal health monitoring and medical diagnosis. These sensors …

Parkinson's disease (PD) is a complex neurological disorder classically characterized by
impairments in motor system function associated with loss of dopaminergic neurons in the …

Biological material is one of the most important aspects that allow for the correct diagnosis of
the disease, and tears are an interesting subject of research because of the simplicity of …

There has been increasing interest in finding non-invasive biomarkers for
neurodegenerative diseases such as Alzheimer's disease (AD). This observational study …

Parkinson's disease (PD) is the most common neurodegenerative disorder with motor
symptoms. The neuropathological alterations characterizing the brain of patients with PD …

The recent validation of the α-synuclein seed amplification assay as a biomarker with high
sensitivity and specificity for the diagnosis of Parkinson's disease has formed the backbone …

Discovery of robust, selective and specific biomarkers are important for early diagnosis and
monitor progression of human diseases. Eye being a common target for several human …