[PDF][PDF] Sex differences in nonalcoholic fatty liver disease: state of the art and identification of research gaps

A Lonardo, F Nascimbeni, S Ballestri… - …, 2019 - Wiley Online Library
Despite tremendous research advancements in nonalcoholic fatty liver disease (NAFLD),
our understanding of sex differences in NAFLD remains insufficient. This review summarizes …

Sexual dimorphism in cardiometabolic health: the role of adipose tissue, muscle and liver

GH Goossens, JWE Jocken, EE Blaak - Nature Reviews Endocrinology, 2021 - nature.com
Obesity is associated with many adverse health effects, such as an increased
cardiometabolic risk. Despite higher adiposity for a given BMI, premenopausal women are at …

Nonalcoholic Fatty Liver Disease (Japanese Version)

XJ Wang, H Malhi - Annals of internal medicine, 2018 - acpjournals.org
非アルコール性脂肪性肝疾患 (NAFLD) は, 慢性肝疾患の主な原因である. 多くはプライマリケアや
病院における肝酵素の上昇や脂肪肝の画像所見により, 偶発的に診断される. NAFLD …

Gender differences in skeletal muscle substrate metabolism–molecular mechanisms and insulin sensitivity

AM Lundsgaard, B Kiens - Frontiers in endocrinology, 2014 - frontiersin.org
It has become increasingly apparent that substrate metabolism is subject to gender-specific
regulation, and the aim of this review is to outline the available evidence of molecular …

Clinical impact of sexual dimorphism in non‐alcoholic fatty liver disease (NAFLD) and non‐alcoholic steatohepatitis (NASH)

P Burra, D Bizzaro, A Gonta, S Shalaby… - Liver …, 2021 - Wiley Online Library
NAFLD/NASH is a sex‐dimorphic disease, with a general higher prevalence in men. Women
are at reduced risk of NAFLD compared to men in fertile age, whereas after menopause …

Sexual dimorphism of NAFLD in adults. Focus on clinical aspects and implications for practice and translational research

A Lonardo, A Suzuki - Journal of clinical medicine, 2020 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) embraces the clinico-pathological consequences
of hepatic lipotoxicity and is a major public health problem globally. Sexual dimorphism is a …

Adiponectin-resistance in obesity

A Engin - Obesity and lipotoxicity, 2017 - Springer
The decrease in adiponectin levels are negatively correlated with chronic subclinical
inflammation markers in obesity. The hypertrophic adipocytes cause obesity-linked insulin …

[PDF][PDF] Metabolism and insulin signaling in common metabolic disorders and inherited insulin resistance

K Højlund - 2014 - ugeskriftet.dk
DANISH MEDICAL JOURNAL 2 insulin resistance in genetic and acquired forms of
lipodystrophies and insulin receptorpathies (5), including rare mutations in genes of post …

Adiponectin resistance in skeletal muscle: pathophysiological implications in chronic heart failure

T Sente, AM Van Berendoncks… - Journal of cachexia …, 2016 - Wiley Online Library
Skeletal muscle wasting is a common complication of chronic heart failure (CHF) and linked
to poor patient prognosis. In recent years, adiponectin was postulated to be centrally …

Molecular mechanisms in skeletal muscle underlying insulin resistance in women who are lean with polycystic ovary syndrome

SL Hansen, PF Svendsen, JF Jeppesen… - The Journal of …, 2019 - academic.oup.com
Context Skeletal muscle molecular mechanisms underlying insulin resistance in women with
polycystic ovary syndrome (PCOS) are poorly understood. Objective To provide insight into …