Tackling Non–Small Cell Lung Cancer in Young Adults: From Risk Factors and Genetic Susceptibility to Lung Cancer Profile and Outcomes

JC Laguna, M Tagliamento, M Lambertini… - American Society of …, 2024 - ascopubs.org
Lung cancer has traditionally been associated with advanced age; however, its increasing
incidence among young adults raises concerning questions regarding its etiology and …

[HTML][HTML] Fertility and reproductive concerns related to the new generation of cancer drugs and the clinical implication for young individuals undergoing treatments for …

H Helgadottir, A Matikas, J Fernebro, JE Frödin… - European Journal of …, 2024 - Elsevier
The treatment landscape of solid tumors has changed markedly in the last years.
Molecularly targeted treatments and immunotherapies have been implemented and have, in …

The safety and efficacy for the treatment of alectinib in a women with ALK-positive lung cancer delivered a healthy male neonate throughout Pregnancy: A case report

M Shang, X Luo, J Wu, ZZ Wang, Q Chen, Y Zhou - Lung Cancer, 2023 - Elsevier
The incidence of lung cancer in pregnancy is increasing because of an increase in cigarette
smoking among young women, air pollution, and advanced maternal age. This is the third …

Effective Use of ALK Inhibitors in EML4:: ALK‐Positive Lymphatic Malformations

B Apsel Winger, CF Dowd, KA Shimano… - Pediatric Blood & …, 2024 - Wiley Online Library
Genetically targeted medications are emerging as important therapies for lymphatic
malformations (LMs) unresponsive to sirolimus. We describe two patients with EML4:: ALK …

Management of a Pregnant ALK-Positive Lung Cancer Patient With Alectinib-Induced Pneumonitis and Bilateral Globus Pallidus Necrosis Postpartum

T Bochtler, P Christopoulos, K Schlamp, F Winkler… - Clinical Lung Cancer, 2024 - Elsevier
Clinical Practice Points• This case highlights the treatment strategies for ALK-positive non–
small-cell lung cancer in pregnant females, where only scarce experience is available yet …

ALK Rearrangement Positive Lung Adenocarcinoma in Pregnancy Treated With Alectinib: A Case Report

LF Gonzalez-Mosquera, FA Rous, A Rogers, N Smith… - Clinical lung cancer, 2024 - Elsevier
There are few reported cases of ALK gene rearranged (ALK+) non–small cell lung cancer
(NSCLC) during pregnancy. There is a lack of information on the safety of ALK inhibitors in …

Anaplastic Lymphoma Kinase-Tyrosine Kinase Inhibitor Treatment for Metastatic Non-small Cell Lung Cancer Throughout the Entire Gestation Period

M Kato, T Yamaura, H Mine, S Kin, H Suzuki - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
Non-small cell lung cancer (NSCLC) occasionally develops in younger, fertile patients. This
early-onset NSCLC tends to have more oncogenic driver mutations than in aged patients …