Oxygen radicals, nitric oxide, and peroxynitrite: Redox pathways in molecular medicine
R Radi - Proceedings of the National Academy of Sciences, 2018 - National Acad Sciences
Oxygen-derived free radicals and related oxidants are ubiquitous and short-lived
intermediates formed in aerobic organisms throughout life. These reactive species …
intermediates formed in aerobic organisms throughout life. These reactive species …
[HTML][HTML] Antioxidant therapy in cancer: Rationale and progress
Cancer is characterized by increased oxidative stress, an imbalance between reactive
oxygen species (ROS) and antioxidants. Enhanced ROS accumulation, as a result of …
oxygen species (ROS) and antioxidants. Enhanced ROS accumulation, as a result of …
[HTML][HTML] Construction of a two-dimensional artificial antioxidase for nanocatalytic rheumatoid arthritis treatment
B Yang, H Yao, J Yang, C Chen, J Shi - Nature Communications, 2022 - nature.com
Constructing nanomaterials mimicking the coordination environments of natural enzymes
may achieve biomimetic catalysis. Here we construct a two-dimensional (2D) metal-organic …
may achieve biomimetic catalysis. Here we construct a two-dimensional (2D) metal-organic …
[HTML][HTML] European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …
Ochratoxin A: Toxicity, oxidative stress and metabolism
Y Tao, S Xie, F Xu, A Liu, Y Wang, D Chen… - Food and Chemical …, 2018 - Elsevier
Ochratoxin A (OTA) is a widespread mycotoxin commonly found as a corn contaminant. It
has been shown to be nephrotoxic, hepatotoxic, teratogenic and immunotoxic to several …
has been shown to be nephrotoxic, hepatotoxic, teratogenic and immunotoxic to several …
Ergothioneine–a diet‐derived antioxidant with therapeutic potential
B Halliwell, IK Cheah, RMY Tang - FEBS letters, 2018 - Wiley Online Library
Ergothioneine is a thiol/thione molecule synthesised only by some fungi and bacteria.
Nonetheless, it is avidly taken up from the diet by humans and other animals through a …
Nonetheless, it is avidly taken up from the diet by humans and other animals through a …
Catalysis and Electron Transfer in De Novo Designed Metalloproteins
One of the hallmark advances in our understanding of metalloprotein function is showcased
in our ability to design new, non-native, catalytically active protein scaffolds. This review …
in our ability to design new, non-native, catalytically active protein scaffolds. This review …
Mini-Review: Oxidative stress, redox stress or redox success?
JMC Gutteridge, B Halliwell - Biochemical and biophysical research …, 2018 - Elsevier
The first life forms evolved in a highly reducing environment. This reduced state is still
carried by cells today, which makes the concept of “reductive stress” somewhat redundant …
carried by cells today, which makes the concept of “reductive stress” somewhat redundant …
The superoxide radical switch in the biology of nitric oxide and peroxynitrite
L Piacenza, A Zeida, M Trujillo… - Physiological …, 2022 - journals.physiology.org
The free radical nitric oxide (· NO) is a key mediator in different physiological processes such
as vasodilation, neurotransmission, inflammation, and cellular immune responses, and thus …
as vasodilation, neurotransmission, inflammation, and cellular immune responses, and thus …
Intracellular catalysis with selected metal complexes and metallic nanoparticles: advances toward the development of catalytic metallodrugs
JJ Soldevila-Barreda, N Metzler-Nolte - Chemical reviews, 2019 - ACS Publications
Platinum-containing drugs (eg, cisplatin) are among the most frequently used
chemotherapeutic agents. Their tremendous success has spurred research and …
chemotherapeutic agents. Their tremendous success has spurred research and …