[HTML][HTML] Circulating MicroRNAs, the next-generation serum biomarkers in testicular germ cell tumours: a systematic review
Context Clinical management of testicular germ cell tumours (GCTs) is hampered by low
sensitivity and specificity of the biomarkers currently in use. Circulating microRNAs (miRs) …
sensitivity and specificity of the biomarkers currently in use. Circulating microRNAs (miRs) …
Versatile role of curcumin and its derivatives in lung cancer therapy
M Ashrafizadeh, M Najafi, P Makvandi… - Journal of cellular …, 2020 - Wiley Online Library
Lung cancer is a main cause of death all over the world with a high incidence rate.
Metastasis into neighboring and distant tissues as well as resistance of cancer cells to …
Metastasis into neighboring and distant tissues as well as resistance of cancer cells to …
Application of miRNAs in the diagnosis and monitoring of testicular germ cell tumours
Testicular germ cell tumours (TGCTs) are the most frequent cancer type in young men and
originate from the common precursor germ cell neoplasia in situ (GCNIS). For decades …
originate from the common precursor germ cell neoplasia in situ (GCNIS). For decades …
Identification and validation model for informative liquid biopsy-based microRNA biomarkers: insights from germ cell tumor in vitro, in vivo and patient-derived data
J Lobo, AJM Gillis, A van den Berg, LCJ Dorssers… - Cells, 2019 - mdpi.com
Liquid biopsy-based biomarkers, such as microRNAs, represent valuable tools for patient
management, but often do not make it to integration in the clinic. We aim to explore issues …
management, but often do not make it to integration in the clinic. We aim to explore issues …
Utility of serum miR-371a-3p in predicting relapse on surveillance in patients with clinical stage I testicular germ cell cancer
J Lobo, R Leao, AJM Gillis, A van den Berg… - European Urology …, 2021 - Elsevier
Background Optimal management of clinical stage I (CSI) testicular cancer is controversial
due to lack of robust prognostic factors; miRNA-371a-3p holds promise as a biomarker …
due to lack of robust prognostic factors; miRNA-371a-3p holds promise as a biomarker …
Refining the serum miR-371a-3p test for viable germ cell tumor detection
JT Lafin, CG Scarpini, A Amini, B Konneh… - Scientific reports, 2023 - nature.com
Abstract Circulating miR-371a-3p has excellent performance in the detection of viable (non-
teratoma) germ cell tumor (GCT) pre-orchiectomy; however, its ability to detect occult …
teratoma) germ cell tumor (GCT) pre-orchiectomy; however, its ability to detect occult …
Integrated expression of circulating miR375 and miR371 to identify teratoma and active germ cell malignancy components in malignant germ cell tumors
Active germ cell malignancies express high levels of specific circulating micro-RNAs
(miRNAs), including miR-371a-3p (miR371), which is undetectable in teratoma. Teratoma …
(miRNAs), including miR-371a-3p (miR371), which is undetectable in teratoma. Teratoma …
Real-world application of pre-orchiectomy miR-371a-3p test in testicular germ cell tumor management
Purpose: Current serum tumor markers for testicular germ cell tumor are limited by low
sensitivity. Growing evidence supports the use of circulating miR-371a-3p as a superior …
sensitivity. Growing evidence supports the use of circulating miR-371a-3p as a superior …
Detection of recurrence through microRNA-371a-3p serum levels in a follow-up of stage I testicular germ cell tumors in the DRKS-00019223 study
G Belge, C Dumlupinar, T Nestler, M Klemke… - Clinical Cancer …, 2024 - AACR
Purpose: Surveillance of clinical stage I (CSI) testicular germ cell tumors (GCT) is hampered
by low sensitivity and specificity of current biomarkers for detecting relapses. This study …
by low sensitivity and specificity of current biomarkers for detecting relapses. This study …
[HTML][HTML] Molecular biomarkers with potential clinical application in testicular cancer
Testicular germ cell tumors (TGCTs) and sex cord-stromal tumors (SCSTs) are the most
common testicular neoplasms. The morphological spectrum of such tumors is wide, with …
common testicular neoplasms. The morphological spectrum of such tumors is wide, with …