The mutational landscape of mucosal melanoma
KW Nassar, AC Tan - Seminars in cancer biology, 2020 - Elsevier
Mucosal melanoma is a rare and aggressive subtype of melanoma that has a less favorable
prognosis due to the lack of understanding and identification of oncogenic drivers. Recently …
prognosis due to the lack of understanding and identification of oncogenic drivers. Recently …
Melanoma: What do all the mutations mean?
EJ Davis, DB Johnson, JA Sosman, S Chandra - Cancer, 2018 - Wiley Online Library
Melanoma is one of the most highly mutated malignancies, largely as a function of its
generation through ultraviolet light and other mutational processes. The wide array of …
generation through ultraviolet light and other mutational processes. The wide array of …
Tertiary lymphoid structures improve immunotherapy and survival in melanoma
Checkpoint blockade therapies that reactivate tumour-associated T cells can induce durable
tumour control and result in the long-term survival of patients with advanced cancers …
tumour control and result in the long-term survival of patients with advanced cancers …
The spatial landscape of progression and immunoediting in primary melanoma at single-cell resolution
Cutaneous melanoma is a highly immunogenic malignancy that is surgically curable at early
stages but life-threatening when metastatic. Here we integrate high-plex imaging, 3D high …
stages but life-threatening when metastatic. Here we integrate high-plex imaging, 3D high …
TMB and inflammatory gene expression associated with clinical outcomes following immunotherapy in advanced melanoma
FS Hodi, JD Wolchok, D Schadendorf, J Larkin… - Cancer Immunology …, 2021 - AACR
Outcomes for patients with melanoma have improved over the past decade as a result of the
development and FDA approval of immunotherapies targeting cytotoxic T lymphocyte …
development and FDA approval of immunotherapies targeting cytotoxic T lymphocyte …
lncRNA CYTOR promotes aberrant glycolysis and mitochondrial respiration via HNRNPC-mediated ZEB1 stabilization in oral squamous cell carcinoma
W Zhu, J Wang, X Liu, Y Xu, R Zhai, J Zhang… - Cell death & …, 2022 - nature.com
Oral squamous cell carcinoma (OSCC), the most common malignancy of the oral and
maxillofacial region, severely affects human health. However, current treatments for OSCC …
maxillofacial region, severely affects human health. However, current treatments for OSCC …
[HTML][HTML] The Tumor Profiler Study: integrated, multi-omic, functional tumor profiling for clinical decision support
The application and integration of molecular profiling technologies create novel
opportunities for personalized medicine. Here, we introduce the Tumor Profiler Study, an …
opportunities for personalized medicine. Here, we introduce the Tumor Profiler Study, an …
[HTML][HTML] Conjunctival melanoma: New insights in tumour genetics and immunology, leading to new therapeutic options
NJ Brouwer, RM Verdijk, S Heegaard… - Progress in Retinal and …, 2022 - Elsevier
Recent developments in oncology have led to a better molecular and cellular understanding
of cancer, and the introduction of novel therapies. Conjunctival melanoma (CoM) is a rare …
of cancer, and the introduction of novel therapies. Conjunctival melanoma (CoM) is a rare …
Dedifferentiated and undifferentiated melanomas: report of 35 new cases with literature review and proposal of diagnostic criteria
A Agaimy, R Stoehr, A Hornung, J Popp… - The American Journal …, 2021 - journals.lww.com
Dedifferentiated melanoma (DM) and undifferentiated melanoma (UM) is defined as a
primary or metastatic melanoma showing transition between conventional and …
primary or metastatic melanoma showing transition between conventional and …
Connecting the dots: melanoma cell of origin, tumor cell plasticity, trans‐differentiation, and drug resistance
E Castro‐Pérez, M Singh, S Sadangi… - Pigment Cell & …, 2023 - Wiley Online Library
Melanoma, a lethal malignancy that arises from melanocytes, exhibits a multiplicity of clinico‐
pathologically distinct subtypes in sun‐exposed and non‐sun‐exposed areas. Melanocytes …
pathologically distinct subtypes in sun‐exposed and non‐sun‐exposed areas. Melanocytes …