Bone tissue is a highly vascularized tissue and concomitant development of the vascular
system and mineralized matrix requires a synergistic interaction between osteogenesis and …

The discovery of osteoinductivity of calcium phosphate (Ca-P) ceramics has set an enduring
paradigm of conferring biological regenerative activity to materials with carefully designed …

Osteoimmunomodulation has informed the importance of modulating a favorable
osteoimmune environment for successful materials-mediated bone regeneration …

Embryogenic developmental processes involve a tightly controlled regulation between
mechanical forces and biochemical cues such as growth factors, matrix proteins, and …

The rapid degradation of magnesium (Mg) alloy implants erodes mechanical performance
and interfacial bioactivity, thereby limiting their clinical utility. Surface modification is among …

The fate of biomaterials is orchestrated by biocompatibility and bioregulation characteristics,
reported to be closely related to topographical structures. For the purpose to investigate the …

Traditional bone replacement materials have been developed with the goal of directing the
osteogenesis of osteoblastic cell lines toward differentiation and therefore achieving …

Research in stomatology (dental medicine) continues to expand globally and is oriented
towards solving clinical issues, focusing on clarifying the clinical relevance and potential …

Wnt/β-catenin signal transduction is involved in the homeostatic control of bone mass. It is
well established that a titanium surface with nanotopography (Ti-Nano) favors osteoblast …

The bone remodeling process is crucial for titanium (Ti) osseointegration and involves the
crosstalk between osteoclasts and osteoblasts. Considering the high osteogenic potential of …